B6;129P2-Dp(17Abcg1-Cbs)1Yah/Orl

Status	Available to order
EMMA ID	EM:01987
International strain name	B6;129P2-Dp(17Abcg1-Cbs)1Yah/Orl
Alternative name	Dup(Abcg1-U2af1) n°138/+
Strain type	Targeted Mutant Strains : Other targeted
Allele/Transgene symbol	Dp(17Abcg1-Cbs)1Yah
Gene/Transgene symbol	Dp(17Abcg1-Cbs)1Yah

Information from provider

Provider	Yann HERAULT
Provider affiliation	TAAM-CDTA UPS44, Institut de Transgenose, INTRAGENE
Genetic information	Duplication of the region between Abcg1-U2af1 genes on the MMU17.
Phenotypic information	No visible phenotype, fertility is normal.
Breeding history	2 backcrosses on C57BL/6.
References	A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome.;Pereira Patricia Lopes, Magnol Laetitia, Sahún Ignasi, Brault Véronique, Duchon Arnaud, Prandini Paola, Gruart Agnès, Bizot Jean-Charles, Chadefaux-Vekemans Bernadette, Deutsch Samuel, Trovero Fabrice, Delgado-García José María, Antonarakis Stylianos E, Dierssen Mara, Herault Yann, ;2009;Human molecular genetics;18;4756-69; 19783846 Rodent models in Down syndrome research: impact and future opportunities.;Herault Yann, Delabar Jean M, Fisher Elizabeth M C, Tybulewicz Victor L J, Yu Eugene, Brault Veronique, ;2017;Disease models & mechanisms;10;1165-1186; 28993310

Information from EMMA

Archiving centre	Institut de Transgenose, INTRAGENE, Orléans, France

Disease and phenotype information

MGI allele-associated human disease models

Down syndrome / DOID:14250

Literature references

A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome.;Pereira Patricia Lopes, Magnol Laetitia, Sahún Ignasi, Brault Véronique, Duchon Arnaud, Prandini Paola, Gruart Agnès, Bizot Jean-Charles, Chadefaux-Vekemans Bernadette, Deutsch Samuel, Trovero Fabrice, Delgado-García José María, Antonarakis Stylianos E, Dierssen Mara, Herault Yann, ;2009;Human molecular genetics;18;4756-69; 19783846
Rodent models in Down syndrome research: impact and future opportunities.;Herault Yann, Delabar Jean M, Fisher Elizabeth M C, Tybulewicz Victor L J, Yu Eugene, Brault Veronique, ;2017;Disease models & mechanisms;10;1165-1186; 28993310

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

Other EMMA strains

Not found what you were looking for? Search here for other strains available from EMMA.