B6;129P2-Dbx1tm2(cre)Apie/Orl

Status

Available to order

EMMA IDEM:01924
International strain nameB6;129P2-Dbx1tm2(cre)Apie/Orl
Alternative nameDbx1CRE
Strain typeTargeted Mutant Strains : Knock-in
Allele/Transgene symbolDbx1tm2(cre)Apie
Gene/Transgene symbolDbx1

Information from provider

ProviderAlessandra Pierani
Provider affiliationInstitut Jacques Monod CNRS UMR 7592
Genetic informationInsertion of an IRES-CRE-pGK-Hygror cassette into the 3-prime-UTR of the Dbx1 gene.
Phenotypic informationNone.
Breeding historyThe strain has been bred into C57BL/6 since 2001.
References
  • Multiple origins of Cajal-Retzius cells at the borders of the developing pallium.;Bielle Franck, Griveau Amélie, Narboux-Nême Nicolas, Vigneau Sébastien, Sigrist Markus, Arber Silvia, Wassef Marion, Pierani Alessandra, ;2005;Nature neuroscience;8;1002-12; 16041369

Information from EMMA

Archiving centreInstitut de Transgenose, INTRAGENE, Orléans, France

Disease and phenotype information

MGI phenotypes (gene matching)
  • abnormal medulla oblongata morphology / MGI
  • cyanosis / MGI
  • respiratory failure / MGI
  • no abnormal phenotype detected / MGI
  • no phenotypic analysis / MGI
  • abnormal GABAergic neuron morphology / MGI
  • abnormal spinal cord interneuron morphology / MGI
  • abnormal somatic nervous system physiology / MGI
  • abnormal pre-Botzinger complex morphology / MGI
  • abnormal pre-Botzinger complex physiology / MGI
  • neonatal lethality, complete penetrance / MGI

Literature references

  • Multiple origins of Cajal-Retzius cells at the borders of the developing pallium.;Bielle Franck, Griveau Amélie, Narboux-Nême Nicolas, Vigneau Sébastien, Sigrist Markus, Arber Silvia, Wassef Marion, Pierani Alessandra, ;2005;Nature neuroscience;8;1002-12; 16041369

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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