B6;SJL-Tg(Vps54)#Mm/Cnrm
| Status | Available to order |
| EMMA ID | EM:01826 |
| Citation information | RRID:IMSR_EM:01826 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;SJL-Tg(Vps54)#Mm/Cnrm |
| Alternative name | Vps54-BAC-tg |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Vps54)#Mm |
| Gene/Transgene symbol | Tg(Vps54)#Mm |
Information from provider
| Provider | Miriam and Thomas Schmitt-John MEISLER |
| Provider affiliation | Aarhus University, Aarhus, Denmark & GBF, Braunschweig, Germany |
| Genetic information | 163kb BAC with wild-type Vps54 allele complete genomic sequence, including flanking regulatory sequences (68kb upstream and 18kb downstream of Vps54-coding sequences). |
| Phenotypic information | No abnormal phenotype found so far. |
| Breeding history | Male founders were mated with wild-type C57BL/6J females or C57BL/6J females heterozygous for the Vps54-wobbler mutation. F1 offspring are intercrossed. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse.;Schmitt-John Thomas, Drepper Carsten, Mussmann Anke, Hahn Phillip, Kuhlmann Melanie, Thiel Cora, Hafner Martin, Lengeling Andreas, Heimann Peter, Jones Julie M, Meisler Miriam H, Jockusch Harald, ;2005;Nature genetics;37;1213-5; 16244655