B6.CD1-Tg(Rho-tTA)5Vmrg/Cnrm

Status	Available to order
EMMA ID	EM:01792
International strain name	B6.CD1-Tg(Rho-tTA)5Vmrg/Cnrm
Alternative name	RhotTA-L5
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(Rho-tTA)5Vmrg
Gene/Transgene symbol	Tg(Rho-tTA)5Vmrg

Information from provider

Provider	Valeria Marigo
Provider affiliation	TIGEM (Telethon Institute of Genetics and Medicine)
Genetic information	This murine line expresses the tTA transactivator in photoreceptor cells of the retina. This allows inducible gene expression in the retina with the tet-off system.
Phenotypic information	Mice do not show defects. Retina electrophysiology of transgenic mice was tested and found normal.
Breeding history	CD1 transgenic mice were crossed to C57BL/6 mice for 10 generations.
References	An in vivo doxycycline-controlled expression system for functional studies of the retina.;Angeletti Barbara, Löster Jana, Auricchio Alberto, Gekeler Florian, Shinoda Kei, Ballabio Andrea, Graw Jochen, Marigo Valeria, ;2003;Investigative ophthalmology & visual science;44;755-60; 12556410

Information from EMMA

Archiving centre	CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Literature references

An in vivo doxycycline-controlled expression system for functional studies of the retina.;Angeletti Barbara, Löster Jana, Auricchio Alberto, Gekeler Florian, Shinoda Kei, Ballabio Andrea, Graw Jochen, Marigo Valeria, ;2003;Investigative ophthalmology & visual science;44;755-60; 12556410

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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