B6.CD1-Tg(Rho-tTA)5Vmrg/Cnrm
Status | Available to order |
EMMA ID | EM:01792 |
Citation information | RRID:IMSR_EM:01792 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | B6.CD1-Tg(Rho-tTA)5Vmrg/Cnrm |
Alternative name | RhotTA-L5 |
Strain type | Transgenic Strains |
Allele/Transgene symbol | Tg(Rho-tTA)5Vmrg |
Gene/Transgene symbol | Tg(Rho-tTA)5Vmrg |
Information from provider
Provider | Valeria Marigo |
Provider affiliation | TIGEM (Telethon Institute of Genetics and Medicine) |
Genetic information | This murine line expresses the tTA transactivator in photoreceptor cells of the retina. This allows inducible gene expression in the retina with the tet-off system. |
Phenotypic information | Mice do not show defects. Retina electrophysiology of transgenic mice was tested and found normal. |
Breeding history | CD1 transgenic mice were crossed to C57BL/6 mice for 10 generations. |
References |
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Information from EMMA
Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- An in vivo doxycycline-controlled expression system for functional studies of the retina.;Angeletti Barbara, Löster Jana, Auricchio Alberto, Gekeler Florian, Shinoda Kei, Ballabio Andrea, Graw Jochen, Marigo Valeria, ;2003;Investigative ophthalmology & visual science;44;755-60; 12556410
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