| Status | Available to order |
| EMMA ID | EM:01789 |
| Citation information | RRID:IMSR_EM:01789 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Axin2tm1Wbm/Ieg |
| Alternative name | Conductin (Axin2)-lacZ |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Axin2tm1Wbm |
| Gene/Transgene symbol | Axin2 |
| Provider | Boris Jerchow |
| Provider affiliation | Max-Delbrueck-Center for Molecular Medicine - HGF |
| Genetic information | Axin2 null mutation. Knock-in of a NLS-lacZ cassette in frame with the ATG start codon of Axin2. Antisense PGK-neo cassette flanked by loxP-sites following the lacZ. Only splice acceptor and donor of first coding exon (exon 2) left. |
| Phenotypic information | Minor defect: craniosynosthosis. |
| Breeding history | Backcrossed to C57BL/6. Number of generations unknown. Currently backcrossed to C57BL/6 and mated to (C57BL/6 x DBA/2)F1 hybrids. |
| References |
|
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
MGI allele-associated human disease models
Orphanet associated rare diseases, based on orthologous gene matching
