B10.Cg-H2^k2 Tg(CD2-Ptpn11*C459S)1Axdr/AxdrH

Status	Available to order
EMMA ID	EM:01734
International strain name	B10.Cg-H2^k2 Tg(CD2-Ptpn11*C459S)1Axdr/AxdrH
Alternative name	Shp2CS x B10.BR Line 1
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(CD2-Ptpn11*C459S)1Axdr
Gene/Transgene symbol	Tg(CD2-Ptpn11*C459S)1Axdr

Information from provider

Provider	Denis Alexander
Provider affiliation	The Babraham Institute, Babraham, Cambridge, CB2 4PB
Phenotypic information	Defective primary immune responses to T-dependent antigen and amplified cytokine secretion in response to antigenic challenge.
References	The src homology 2 domain-containing tyrosine phosphatase 2 regulates primary T-dependent immune responses and Th cell differentiation.;Salmond Robert J, Huyer Gregory, Kotsoni Anastasia, Clements Lisa, Alexander Denis R, ;2005;Journal of immunology (Baltimore, Md. : 1950);175;6498-508; 16272304

Information from EMMA

Archiving centre	Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Literature references

The src homology 2 domain-containing tyrosine phosphatase 2 regulates primary T-dependent immune responses and Th cell differentiation.;Salmond Robert J, Huyer Gregory, Kotsoni Anastasia, Clements Lisa, Alexander Denis R, ;2005;Journal of immunology (Baltimore, Md. : 1950);175;6498-508; 16272304

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*
Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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B10.Cg-H2k2 Tg(CD2-Ptpn11*C459S)1Axdr/AxdrH