IMPC phenotypes (gene matching)
B6J;129S1-Capn5tm1Nde/H
| Status | Available to order |
| EMMA ID | EM:01718 |
| International strain name | B6J;129S1-Capn5tm1Nde/H |
| Alternative name | Capn5 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Capn5tm1Nde |
| Gene/Transgene symbol | Capn5 |
Information from provider
| Provider | Neil Dear |
| Provider affiliation | MRC Mammalian Genetics Unit |
| Genetic information | An IRES-lacZ-neomycin cassette was inserted into exon 4 of the Capn5 gene by homologous recombination. |
| Phenotypic information | CAPN5 is a protease expressed in T cells. The Capn5 gene has been inactivated in this mouse strain. |
| References |
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Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal dominant neovascular inflammatory vitreoretinopathy / Orphanet_329211
Literature references
- Capn5 is expressed in a subset of T cells and is dispensable for development.;Franz Tanna, Winckler Lara, Boehm Thomas, Dear T Neil, ;2004;Molecular and cellular biology;24;1649-54; 14749380