IMPC phenotypes (gene matching)
B6J;129S1-Capn5tm1Nde/H
| Status | Available to order |
| EMMA ID | EM:01718 |
| Citation information | RRID:IMSR_EM:01718 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6J;129S1-Capn5tm1Nde/H |
| Alternative name | Capn5 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Capn5tm1Nde |
| Gene/Transgene symbol | Capn5 |
Information from provider
| Provider | Neil Dear |
| Provider affiliation | MRC Mammalian Genetics Unit |
| Genetic information | An IRES-lacZ-neomycin cassette was inserted into exon 4 of the Capn5 gene by homologous recombination. |
| Phenotypic information | CAPN5 is a protease expressed in T cells. The Capn5 gene has been inactivated in this mouse strain. |
| References |
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Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal dominant neovascular inflammatory vitreoretinopathy / Orphanet_329211
Literature references
- Capn5 is expressed in a subset of T cells and is dispensable for development.;Franz Tanna, Winckler Lara, Boehm Thomas, Dear T Neil, ;2004;Molecular and cellular biology;24;1649-54; 14749380