C57BL/6N-Mrpl39em1(IMPC)Ics/Ics

Status

Available to order

EMMA IDEM:15790
International strain nameC57BL/6N-Mrpl39em1(IMPC)Ics/Ics
Alternative nameMrpl39em1(IMPC)Ics
Strain typeEndonuclease-mediated
Allele/Transgene symbolMrpl39em1(IMPC)Ics
Gene/Transgene symbolMrpl39

Information from provider

Provider ICS, Institut Clinique de la Souris
Provider affiliationICS, Institut Clinique de la Souris
Genetic informationThis allele was generated at the Institute Clinique de la Souris by electroporating Cas9 protein and 4 RNA guides (sequences: AGAGAAACAACGTGAATCCA, ATTGTGGGTACATCAATCCA, GGATAACCCTCTAAATCATC and GGGACTCCCGATGATTTAGA), which resulted in a 737 bp deletion on Chromosome 16. This mutation deletes exon 3 (ENSMUSE00000131646; GRCm39), leading to a frameshift with a premature stop. This line is cryopreserved.
Phenotypic informationHomozygous:
NA

Heterozygous:
Viable, no obvious phenotype
Breeding historyThis line was generated on a pure C57BL/6N genetic background.
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

Disease and phenotype information

IMPC phenotypes (gene matching)
  • decreased circulating creatinine level / IMPC
  • preweaning lethality, complete penetrance / IMPC
  • decreased circulating bilirubin level / IMPC
  • increased circulating glucose level / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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