C57BL/6NCrl-Wnt4em1(IMPC)Hmgu/Ieg

Status

Available to order

EMMA IDEM:15721
International strain nameC57BL/6NCrl-Wnt4em1(IMPC)Hmgu/Ieg
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolWnt4em1(IMPC)Hmgu
Gene/Transgene symbolWnt4

Information from provider

Provider Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Provider affiliationInstitute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archivingheterozygous C57BL/6N

Disease and phenotype information

MGI phenotypes (gene matching)
  • absent kidney / MGI
  • abnormal kidney development / MGI
  • delayed kidney development / MGI
  • decreased thymocyte number / MGI
  • abnormal ovary morphology / MGI
  • abnormal oogenesis / MGI
  • secondary sex reversal / MGI
  • no abnormal phenotype detected / MGI
  • abnormal secondary sex determination / MGI
  • abnormal adrenal gland physiology / MGI
  • no phenotypic analysis / MGI
  • kidney failure / MGI
  • nervous system phenotype / MGI
  • abnormal reproductive system development / MGI
  • abnormal adenohypophysis morphology / MGI
  • decreased renal glomerulus number / MGI
  • decreased oocyte number / MGI
  • abnormal female germ cell morphology / MGI
  • absent Mullerian ducts / MGI
  • decreased somatotroph cell number / MGI
  • decreased gonadotroph cell number / MGI
  • decreased thyrotroph cell number / MGI
  • oocyte degeneration / MGI
  • abnormal metanephric mesenchyme morphology / MGI
  • abnormal nephrogenic mesenchyme morphogenesis / MGI
  • postnatal lethality, complete penetrance / MGI
  • neonatal lethality, complete penetrance / MGI
  • small metanephros / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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