C57BL/6J-Pcdh19em2H/H
| Status | Available to order |
| EMMA ID | EM:15699 |
| International strain name | C57BL/6J-Pcdh19em2H/H |
| Alternative name | C57BL/6J-Pcdh19 |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Pcdh19em2H |
| Gene/Transgene symbol | Pcdh19 |
Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | As reported by Mouse Genome Informatics, Pcdh19, a protein coding gene, codes for protocadherin-19 and is associated with developmental and epileptic encephalopathy in Humans. This line was generated by introducing a Knock-in of ddCre into the 5' UTR of Pcdh19 made by CRISPR/Cas9 gene editing. The knock-in was introduced via pronuclear injection into 1-cell stage embryo. |
| Phenotypic information | Homozygous:To be determinedHeterozygous:To be determined |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |