C57BL/6J-Nelfeem1H/H

Status

Available to order

EMMA IDEM:15698
International strain nameC57BL/6J-Nelfeem1H/H
Alternative name C57BL/6J-Nelfe/H
Strain typeEndonuclease-mediated
Allele/Transgene symbolNelfeem1H
Gene/Transgene symbolNelfe

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationAs reported by Mouse Genome Informatics, Nelfe, a protein coding gene, codes for negative elongation factor E. This is a Floxed allele made using CRISPR/Cas9. Floxing of exons ENSMUSE00000141419 and ENSMUSE00001249621 was done via pronuclear injection into 2-cell stage embryo.
Phenotypic informationHomozygous:
To be determined

Heterozygous:
To be determined
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (gene matching)
  • preweaning lethality, complete penetrance / IMPC
  • increased grip strength / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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