B6;CB-Mesp1tm2(cre)Ysa/H
| Status | Available to order |
| EMMA ID | EM:15684 |
| International strain name | B6;CB-Mesp1tm2(cre)Ysa/H |
| Alternative name | B6;CB-Mesp1 |
| Strain type | Targeted Mutant Strains : Other targeted |
| Allele/Transgene symbol | Mesp1tm2(cre)Ysa |
| Gene/Transgene symbol |
Information from provider
| Provider | Yumiko Saga |
| Provider affiliation | Cellular and Molecular Toxicology Division, National Institute of Health Sciences |
| Genetic information | Mesp1, a protein coding gene, codes for mesorderm posterior protein1. Its human ortholg MESP1, is associated with myocardial infarction in humans. A Cre gene and pgk-neo cassette were ligated in frame at a NcoI site located at the translational initiation site of the gene, creating a knock-in vector in which cre recombinase was expressed under the control of the endogenous promoter-enhancer. |
| Phenotypic information | Homozygous:No phenotypic description reportedHeterozygous:No phenotypic description reported |
| Breeding history | Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1 No reported breeding issues. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube.;Saga Y, Miyagawa-Tomita S, Takagi A, Kitajima S, Miyazaki J i, Inoue T, ;1999;Development (Cambridge, England);126;3437-47; 10393122