B6;CB-Mesp1tm2(cre)Ysa/H
| Status | Available to order |
| EMMA ID | EM:15684 |
| Citation information | RRID:IMSR_EM:15684 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;CB-Mesp1tm2(cre)Ysa/H |
| Alternative name | B6;CB-Mesp1 |
| Strain type | Targeted Mutant Strains : Other targeted |
| Allele/Transgene symbol | Mesp1tm2(cre)Ysa |
| Gene/Transgene symbol |
Information from provider
| Provider | Yumiko Saga |
| Provider affiliation | Cellular and Molecular Toxicology Division, National Institute of Health Sciences |
| Genetic information | Mesp1, a protein coding gene, codes for mesorderm posterior protein1. Its human ortholg MESP1, is associated with myocardial infarction in humans. A Cre gene and pgk-neo cassette were ligated in frame at a NcoI site located at the translational initiation site of the gene, creating a knock-in vector in which cre recombinase was expressed under the control of the endogenous promoter-enhancer. |
| Phenotypic information | Homozygous:No phenotypic description reportedHeterozygous:No phenotypic description reported |
| Breeding history | Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1 No reported breeding issues. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube.;Saga Y, Miyagawa-Tomita S, Takagi A, Kitajima S, Miyazaki J i, Inoue T, ;1999;Development (Cambridge, England);126;3437-47; 10393122