C57BL/6J-Taslem3H/H

Status

Available to order

EMMA IDEM:15590
International strain nameC57BL/6J-Taslem3H/H
Alternative nameC57BL/6J-Taslem3H/H
Strain typeEndonuclease-mediated
Allele/Transgene symbolTaslem3H
Gene/Transgene symbolTasl

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationAs reported by Mouse Genome Informatics, Tasl, a protein coding gene, codes for TLR adapter interacting with SLC15A4 on the lysosome and is an ortholog for human TASL. This mouse strain carries a CRISPR/Cas9 induced mutation deleting 10 nucleotides of the Tasl gene (in exon ENSMUSE00000697605) via microinjection of reagents into 1-cell stage embryos. This line is X-LINKED.
Phenotypic informationHomozygous:
To be confirmed

Heterozygous:
To be confirmed
Breeding historyIncepient congenic on maintained background
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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