IMPC phenotypes (gene matching)
C57BL/6J-Flncem1H/H
| Status | Available to order |
| EMMA ID | EM:15586 |
| Citation information | RRID:IMSR_EM:15586 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6J-Flncem1H/H |
| Alternative name | C57BL/6J-Flncem1H/H |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Flncem1H |
| Gene/Transgene symbol | Flnc |
Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | As reported by Mouse Genome Informatics, Flnc, a protein coding gene, codes for filamin C and is associated with myofibrillar myopathy in both mice and humans and distal myopathy, and hypertrophic cardiomypathy in humans. This is a CRISPR/Cas9 induced targeted deletion of exon 40 of the Flnc gene via cytoplasmic injection of CRISPR/Cas9 reagents into 2-cell stage embryos. |
| Phenotypic information | Homozygous:To be confirmedHeterozygous:To be confirmed |
| Breeding history | Incepient congenic on maintained background |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |