IMPC phenotypes (gene matching)
C57BL/6J-Flncem1H/H
| Status | Available to order |
| EMMA ID | EM:15586 |
| International strain name | C57BL/6J-Flncem1H/H |
| Alternative name | C57BL/6J-Flncem1H/H |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Flncem1H |
| Gene/Transgene symbol | Flnc |
Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | As reported by Mouse Genome Informatics, Flnc, a protein coding gene, codes for filamin C and is associated with myofibrillar myopathy in both mice and humans and distal myopathy, and hypertrophic cardiomypathy in humans. This is a CRISPR/Cas9 induced targeted deletion of exon 40 of the Flnc gene via cytoplasmic injection of CRISPR/Cas9 reagents into 2-cell stage embryos. |
| Phenotypic information | Homozygous:To be confirmedHeterozygous:To be confirmed |
| Breeding history | Incepient congenic on maintained background |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |