C57BL/6NCrl-Mta1em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:15453
Citation informationRRID:IMSR_EM:15453 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Mta1em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolMta1em1(IMPC)Ccpcz
Gene/Transgene symbolMta1

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (gene matching)
  • increased thermal nociceptive threshold / IMPC
  • abnormal skin morphology / IMPC
  • abnormal skin pigmentation / IMPC
  • abnormal tail morphology / IMPC
  • decreased lumbar vertebrae number / IMPC
  • abnormal behavior / IMPC
  • decreased sacral vertebrae number / IMPC
  • decreased mean corpuscular volume / IMPC
  • absent pinna reflex / IMPC
  • decreased caudal vertebrae number / IMPC
  • abnormal rib morphology / IMPC
  • abnormal bone mineralization / IMPC
  • decreased body weight / IMPC
  • decreased circulating LDL cholesterol level / IMPC
  • increased lean body mass / IMPC
  • trunk curl / IMPC
MGI phenotypes (gene matching)
  • decreased circulating LDL cholesterol level / MGI
  • decreased caudal vertebrae number / MGI
  • increased circulating triglyceride level / MGI
  • abnormal bone mineralization / MGI
  • thrombocytopenia / MGI
  • increased cellular sensitivity to ionizing radiation / MGI
  • decreased lumbar vertebrae number / MGI
  • abnormal behavior / MGI
  • vision/eye phenotype / MGI
  • abnormal retinal development / MGI
  • increased sacral vertebrae number / MGI

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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