C57BL/6NCrl-Gzmbem1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:15452
International strain nameC57BL/6NCrl-Gzmbem1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolGzmbem1(IMPC)Ccpcz
Gene/Transgene symbolGzmb

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

MGI phenotypes (gene matching)
  • abnormal immune system physiology / MGI
  • decreased tumor growth/size / MGI
  • impaired natural killer cell mediated cytotoxicity / MGI
  • decreased cytotoxic T cell cytolysis / MGI
  • immune system phenotype / MGI
  • abnormal enzyme/coenzyme activity / MGI
  • decreased T cell apoptosis / MGI
  • increased sensitivity to induced morbidity/mortality / MGI
  • abnormal NK cell physiology / MGI

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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