C57BL/6NTac-Tmem94tm1c(EUCOMM)Wtsi/IcsOrl

Status

Available to order

EMMA IDEM:15448
Citation informationRRID:IMSR_EM:15448 

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International strain nameC57BL/6NTac-Tmem94tm1c(EUCOMM)Wtsi/IcsOrl
Alternative nameC57BL/6NTac-Tmem94tm1c(EUCOMM)Wtsi/IcsOrl
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolTmem94tm1c(EUCOMM)Wtsi
Gene/Transgene symbolTmem94

Information from provider

ProviderCécile FREMOND
Provider affiliationCNRS-TAAM-UAR44
Genetic informationThis mouse line originates from EUCOMM ES clone EPD0215_1_D09. For further details on the construction of this clone see the page at the IMPC portal. Mice carrying the Tmem94-tm1a(EUCOMM)Wtsi allele have been crossed to flp expressing mice (B6N Gt(ROSA)26Sor-tm2(CAG-flpo,-EYFP)Ics) to obtain the Tmem94-tm1c(EUCOMM)Wtsi allele.
Phenotypic informationHomozygous:
Homozygous mice have not been generated.

Heterozygous:
We did not observe any significant phenotype.
Breeding historyRederived mice carrying the Tmem94tm1a(EUCOMM)Wtsi allele, were crossed to flp recombinase deleter mice (B6N Gt(ROSA)26Sortm2(CAG-flpo,-EYFP)Ics, EMMA strain EM:05490) to obtain the Tmem94tm1c(EUCOMM)Wtsi allele.
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreInstitut de Transgenose, INTRAGENE, Orléans, France
Animals used for archivingheterozygous C57BL/6NTac males

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

    • TMEM94-associated congenital heart defect-facial dysmorphism-developmental delay syndrome / Orphanet_562569
IMPC phenotypes (gene matching)
  • increased mean corpuscular hemoglobin concentration / IMPC
  • preweaning lethality, complete penetrance / IMPC
  • decreased circulating sodium level / IMPC
  • abnormal tail movements / IMPC

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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