C57BL/6NTac-Tmem94tm1c(EUCOMM)Wtsi/IcsOrl
Status | Under development - register interest |
EMMA ID | EM:15448 |
International strain name | C57BL/6NTac-Tmem94tm1c(EUCOMM)Wtsi/IcsOrl |
Alternative name | C57BL/6NTac-Tmem94tm1c(EUCOMM)Wtsi/IcsOrl |
Strain type | Targeted Mutant Strains : Conditional mutation |
Allele/Transgene symbol | Tmem94tm1c(EUCOMM)Wtsi |
Gene/Transgene symbol | Tmem94 |
Information from provider
Provider | Cécile FREMOND |
Provider affiliation | CNRS-TAAM-UAR44 |
Genetic information | This mouse line originates from EUCOMM ES clone EPD0215_1_D09. For further details on the construction of this clone see the page at the IMPC portal. Mice carrying the Tmem94-tm1a(EUCOMM)Wtsi allele have been crossed to flp expressing mice (B6N Gt(ROSA)26Sor-tm2(CAG-flpo,-EYFP)Ics) to obtain the Tmem94-tm1c(EUCOMM)Wtsi allele. |
Phenotypic information | Homozygous:Homozygous mice have not been generated.Heterozygous:We did not observe any significant phenotype. |
Breeding history | Rederived mice carrying the Tmem94tm1a(EUCOMM)Wtsi allele, were crossed to flp recombinase deleter mice (B6N Gt(ROSA)26Sortm2(CAG-flpo,-EYFP)Ics, EMMA strain EM:05490) to obtain the Tmem94tm1c(EUCOMM)Wtsi allele. |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Animals used for archiving | heterozygous C57BL/6NTac |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- TMEM94-associated congenital heart defect-facial dysmorphism-developmental delay syndrome / Orphanet_562569
IMPC phenotypes (gene matching)
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