C57BL/6N-A^tm1Brd Adamdec1^{tm1a(KOMP)Wtsi}/Ics

Status	Available to order
EMMA ID	EM:15307
International strain name	C57BL/6N-A^tm1Brd Adamdec1^{tm1a(KOMP)Wtsi}/Ics
Alternative name	Adamdec1 tm1a(KOMP)Wtsi / MGI:1917650
Strain type	Targeted Mutant Strains
Allele/Transgene symbol	Adamdec1^{tm1a(KOMP)Wtsi}
Gene/Transgene symbol	Adamdec1

Information from provider

Provider	Christopher G. Mueller
Provider affiliation	Institut de Biologie Moléculaire et Cellulaire (IBMC), Immunologie, Immunopathologie et Chimie Thérapeutique - CNRS UPR 3572 Université de Strasbourg
Genetic information	IMPC ES cells have been used to create Adamdec1^{tm1a(KOMP)Wtsi} (https://www.mousephenotype.org/data/alleles/MGI:1917650/tm1a(KOMP)Wtsi). The heterozygous mice have not been crossed with flp deleter mice to obtain Adamdec1^{tm1c(KOMP)Wtsi}.
Phenotypic information	Homozygous: Unknown Heterozygous: None
Breeding history	The Adamdec1^{tm1a(KOMP)Wtsi} mice have not been backcrossed.
References	The ADAMDEC1 (decysin) gene structure: evolution by duplication in a metalloprotease gene cluster on chromosome 8p12.;Bates Elizabeth E M, Fridman Wolf H, Mueller Chris G F, ;2002;Immunogenetics;54;96-105; 12037602 Polymerase chain reaction selects a novel disintegrin proteinase from CD40-activated germinal center dendritic cells.;Mueller C G, Rissoan M C, Salinas B, Ait-Yahia S, Ravel O, Bridon J M, Briere F, Lebecque S, Liu Y J, ;1997;The Journal of experimental medicine;186;655-63; 9271581 Mannose receptor ligand-positive cells express the metalloprotease decysin in the B cell follicle.;Mueller C G, Cremer I, Paulet P E, Niida S, Maeda N, Lebeque S, Fridman W H, Sautès-Fridman C, ;2001;Journal of immunology (Baltimore, Md. : 1950);167;5052-60; 11673514
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

Literature references

The ADAMDEC1 (decysin) gene structure: evolution by duplication in a metalloprotease gene cluster on chromosome 8p12.;Bates Elizabeth E M, Fridman Wolf H, Mueller Chris G F, ;2002;Immunogenetics;54;96-105; 12037602
Polymerase chain reaction selects a novel disintegrin proteinase from CD40-activated germinal center dendritic cells.;Mueller C G, Rissoan M C, Salinas B, Ait-Yahia S, Ravel O, Bridon J M, Briere F, Lebecque S, Liu Y J, ;1997;The Journal of experimental medicine;186;655-63; 9271581
Mannose receptor ligand-positive cells express the metalloprotease decysin in the B cell follicle.;Mueller C G, Cremer I, Paulet P E, Niida S, Maeda N, Lebeque S, Fridman W H, Sautès-Fridman C, ;2001;Journal of immunology (Baltimore, Md. : 1950);167;5052-60; 11673514

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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C57BL/6N-Atm1Brd Adamdec1tm1a(KOMP)Wtsi/Ics