B6Brd;B6N-Tyr^c-Brd Krt76^{tm1a(KOMP)Wtsi}/WtsiPh

Under development - register interest

1. We can not guarantee a null mutation for Knock-out first alleles (tm1a alleles, see http://www.mousephenotype.org/about-ikmc/targeting-strategies) as the critical exon has not been deleted.
2. That the structure of the targeted mutation in the ES cells obtained from EUCOMM/KOMP to generate EUCOMM/KOMP mice is not verified by INFRAFRONTIER/EMMA. It is recommended that the recipient confirms the mutation structure.
3. No check for determining the copy number of the targeting construct in ES cells obtained from EUCOMM/KOMP is done by INFRAFRONTIER/EMMA.
4. The level of quality control before mice are released is to confirm the individual mouse genotype by short range PCR.

• Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.;Liakath-Ali Kifayathullah, Vancollie Valerie E, Heath Emma, Smedley Damian P, Estabel Jeanne, Sunter David, Ditommaso Tia, White Jacqueline K, Ramirez-Solis Ramiro, Smyth Ian, Steel Karen P, Watt Fiona M, ;2014;Nature communications;5;3540; 24721909
• Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse.;DiTommaso Tia, Jones Lynelle K, Cottle Denny L, null null, Gerdin Anna-Karin, Vancollie Valerie E, Watt Fiona M, Ramirez-Solis Ramiro, Bradley Allan, Steel Karen P, Sundberg John P, White Jacqueline K, Smyth Ian M, ;2014;PLoS genetics;10;e1004705; 25340873