- increased leukocyte cell number / IMPC
- increased circulating alanine transaminase level / IMPC
- decreased lean body mass / IMPC
- abnormal humerus morphology / IMPC
- increased circulating aspartate transaminase level / IMPC
- decreased circulating creatinine level / IMPC
- increased mean corpuscular hemoglobin / IMPC
B6Brd;B6N-Tyrc-Brd Dusp3tm1a(KOMP)Wtsi/WtsiOrl
Status | Available to order |
EMMA ID | EM:15208 |
International strain name | B6Brd;B6N-Tyrc-Brd Dusp3tm1a(KOMP)Wtsi/WtsiOrl |
Alternative name | EPD0090_4_H11 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Dusp3tm1a(KOMP)Wtsi |
Gene/Transgene symbol | Dusp3 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from KOMP ES clone EPD0090_4_H11. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References |
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Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- decreased grip strength / IMPC
- increased circulating glycerol level / IMPC
- increased mean corpuscular hemoglobin / IMPC
- increased circulating aspartate transaminase level / IMPC
- decreased lean body mass / IMPC
- decreased circulating creatinine level / IMPC
- increased leukocyte cell number / IMPC
- abnormal humerus morphology / IMPC
- increased circulating alanine transaminase level / IMPC
- decreased red blood cell distribution width / IMPC
- decreased bone mineral content / IMPC
- increased circulating insulin level / IMPC
MGI phenotypes (allele matching)
- decreased circulating creatinine level / MGI
Literature references
- Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes.;White Jacqueline K, Gerdin Anna-Karin, Karp Natasha A, Ryder Ed, Buljan Marija, Bussell James N, Salisbury Jennifer, Clare Simon, Ingham Neil J, Podrini Christine, Houghton Richard, Estabel Jeanne, Bottomley Joanna R, Melvin David G, Sunter David, Adams Niels C, null null, Tannahill David, Logan Darren W, Macarthur Daniel G, Flint Jonathan, Mahajan Vinit B, Tsang Stephen H, Smyth Ian, Watt Fiona M, Skarnes William C, Dougan Gordon, Adams David J, Ramirez-Solis Ramiro, Bradley Allan, Steel Karen P, ;2013;Cell;154;452-64; 23870131
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