C57BL/6NCrl-Chst11em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:15165
International strain nameC57BL/6NCrl-Chst11em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolChst11em1(IMPC)Ccpcz
Gene/Transgene symbolChst11

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (gene matching)
  • preweaning lethality, complete penetrance / IMPC
MGI phenotypes (gene matching)
  • short mandible / MGI
  • short maxilla / MGI
  • cleft palate / MGI
  • abnormal vertebrae morphology / MGI
  • abnormal cartilage morphology / MGI
  • abnormal long bone hypertrophic chondrocyte zone / MGI
  • domed cranium / MGI
  • short limbs / MGI
  • abnormal thymus morphology / MGI
  • respiratory distress / MGI
  • disproportionate dwarf / MGI
  • abnormal Mullerian duct morphology / MGI
  • small scapula / MGI
  • short nasal bone / MGI
  • abnormal vertebral arch morphology / MGI
  • decreased length of long bones / MGI
  • abnormal vertebral column morphology / MGI
  • abnormal talus morphology / MGI
  • abnormal phalanx morphology / MGI
  • abnormal epiphyseal plate morphology / MGI
  • increased diameter of long bones / MGI
  • small thoracic cage / MGI
  • bicuspid aortic valve / MGI
  • cerebral arteriovenous malformation / MGI
  • neonatal lethality, complete penetrance / MGI
  • double ureter / MGI
  • umbilical vein stenosis / MGI
  • ductus venosus stenosis / MGI
  • hepatic portal vein stenosis / MGI
  • abnormal perichondrial ossification / MGI
  • abnormal eye muscle topology / MGI
  • abnormal vitelline vein connection / MGI
  • blood in lymph vessels / MGI
  • abnormal vitelline vein topology / MGI
  • abnormal vertebral artery topology / MGI
  • additional anastomosis between intracranial vertebral arteries / MGI
  • embryo cyst / MGI
  • short facial bone / MGI
  • short ilium / MGI
  • wide ilium / MGI

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

    Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

    * In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

    More details on pricing and delivery times

    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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