C57BL/6NCrl-Suz12em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:15161
International strain nameC57BL/6NCrl-Suz12em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolSuz12em1(IMPC)Ccpcz
Gene/Transgene symbolSuz12

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • increased leukocyte cell number / MGI
  • decreased cell proliferation / MGI
  • hindlimb paralysis / MGI
  • increased inferior colliculus size / MGI
  • decreased corpus callosum size / MGI
  • abnormal cerebral cortex morphology / MGI
  • abnormal stratification in cerebral cortex / MGI
  • abnormal hippocampus morphology / MGI
  • abnormal cerebellum morphology / MGI
  • increased superior colliculus size / MGI
  • abnormal posture / MGI
  • decreased embryo size / MGI
  • embryonic growth arrest / MGI
  • hydroencephaly / MGI
  • abnormal developmental patterning / MGI
  • abnormal extraembryonic tissue morphology / MGI
  • abnormal brain morphology / MGI
  • abnormal chorion morphology / MGI
  • vertebral transformation / MGI
  • spina bifida / MGI
  • abnormal embryonic neuroepithelium morphology / MGI
  • cervical vertebral transformation / MGI
  • lumbar vertebral transformation / MGI
  • thoracic vertebral transformation / MGI
  • increased lymphocyte cell number / MGI
  • abnormal amnion morphology / MGI
  • thrombocytosis / MGI
  • enlarged tectum / MGI
  • increased histiocytic sarcoma incidence / MGI
  • embryonic lethality, complete penetrance / MGI
  • embryonic lethality between somite formation and embryo turning, complete penetrance / MGI
  • embryonic lethality during organogenesis, complete penetrance / MGI
  • preweaning lethality, complete penetrance / MGI
  • abnormal amniotic cavity morphology / MGI
  • abnormal extraembryonic coelom morphology / MGI
  • abnormal ectoplacental cavity morphology / MGI
  • diastematomyelia / MGI
  • increased embryonic tissue cell apoptosis / MGI

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

    Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

    * In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

    More details on pricing and delivery times

    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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