IMPC phenotypes (gene matching)
C57BL/6NCrl-Jarid2em1(IMPC)Ccpcz/Ph
| Status | Under development - register interest |
| EMMA ID | EM:15148 |
| International strain name | C57BL/6NCrl-Jarid2em1(IMPC)Ccpcz/Ph |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Jarid2em1(IMPC)Ccpcz |
| Gene/Transgene symbol | Jarid2 |
Information from provider
| Provider | Institute of Molecular Genetics |
| Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Non-specific syndromic intellectual disability / Orphanet_528084
MGI phenotypes (gene matching)
- abnormal sternum morphology / MGI
- abnormal erythropoiesis / MGI
- abnormal heart development / MGI
- abnormal myocardial fiber morphology / MGI
- abnormal interventricular septum morphology / MGI
- double outlet right ventricle / MGI
- distended pericardium / MGI
- trabecula carnea hypoplasia / MGI
- abnormal liver morphology / MGI
- liver hypoplasia / MGI
- small liver / MGI
- enlarged liver sinusoidal spaces / MGI
- decreased hepatocyte number / MGI
- abnormal liver physiology / MGI
- spleen hypoplasia / MGI
- incomplete rostral neuropore closure / MGI
- anemia / MGI
- hepatic necrosis / MGI
- decreased embryo size / MGI
- edema / MGI
- thymus hypoplasia / MGI
- hemorrhage / MGI
- respiratory failure / MGI
- prenatal lethality / MGI
- abnormal definitive hematopoiesis / MGI
- abnormal neural tube morphology / MGI
- abnormal myocardial trabeculae morphology / MGI
- abnormal megakaryocyte progenitor cell morphology / MGI
- delayed neural tube closure / MGI
- thin myocardium / MGI
- abnormal fetal cardiomyocyte proliferation / MGI
- nervous system phenotype / MGI
- abnormal neural tube closure / MGI
- abnormal nervous system development / MGI
- abnormal heart left ventricle morphology / MGI
- abnormal interventricular groove morphology / MGI
- abnormal myocardium compact layer morphology / MGI
- dilated heart right atrium / MGI
- fetal growth retardation / MGI
- abnormal thoracic cage morphology / MGI
- abnormal neural fold formation / MGI
- abnormal myocardium layer morphology / MGI
- increased circulating creatinine level / MGI
- abnormal neural plate morphology / MGI
- abnormal splenic cell ratio / MGI
- abnormal thymus cell ratio / MGI
- ventricular septal defect / MGI
- abnormal coronary vessel morphology / MGI
- perinatal lethality, complete penetrance / MGI
- embryonic lethality during organogenesis, complete penetrance / MGI
- lethality throughout fetal growth and development, complete penetrance / MGI
- embryonic lethality during organogenesis, incomplete penetrance / MGI
- lethality throughout fetal growth and development, incomplete penetrance / MGI
- decreased fetal derived definitive erythrocyte cell number / MGI