C57BL/6J-Rrm2bem1H/H
| Status | Available to order |
| EMMA ID | EM:15134 |
| International strain name | C57BL/6J-Rrm2bem1H/H |
| Alternative name | RRM2B-Q284X-EM1-B6 |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Rrm2bem1H |
| Gene/Transgene symbol | Rrm2b |
Information from provider
| Provider | MRC-Harwell |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
| Breeding history | Co-isogenic on original background |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Kearns-Sayre syndrome / Orphanet_480
- Autosomal dominant progressive external ophthalmoplegia / Orphanet_254892
- Mitochondrial neurogastrointestinal encephalomyopathy / Orphanet_298
- Adult-onset chronic progressive external ophthalmoplegia with mitochondrial myopathy / Orphanet_329336
- Mitochondrial DNA depletion syndrome, encephalomyopathic form with renal tubulopathy / Orphanet_255235