- malocclusion / MGI
- abnormal cell death / MGI
- abnormal foregut morphology / MGI
- absent floor plate / MGI
- absent notochord / MGI
- decreased body size / MGI
- abnormal eye development / MGI
- circling / MGI
- abnormal gait / MGI
- hunched posture / MGI
- impaired righting response / MGI
- increased circulating triglyceride level / MGI
- increased circulating free fatty acid level / MGI
- absent mesoderm / MGI
- abnormal endoderm development / MGI
- abnormal somite development / MGI
- abnormal somite shape / MGI
- decreased embryo size / MGI
- reduced female fertility / MGI
- abnormal glucose homeostasis / MGI
- postnatal lethality / MGI
- premature death / MGI
- abnormal developmental patterning / MGI
- abnormal embryonic tissue morphology / MGI
- abnormal neural tube morphology / MGI
- no abnormal phenotype detected / MGI
- abnormal primitive streak formation / MGI
- kinked neural tube / MGI
- abnormal nervous system development / MGI
- abnormal craniofacial development / MGI
- abnormal miscarriage rate / MGI
- long incisors / MGI
- abnormal rostral-caudal axis patterning / MGI
- abnormal metabolism / MGI
- abnormal paraxial mesoderm morphology / MGI
- absent estrous cycle / MGI
- absent estrus / MGI
- absent primitive node / MGI
- increased liver triglyceride level / MGI
- abnormal neuron differentiation / MGI
- mortality/aging / MGI
- neonatal lethality, incomplete penetrance / MGI
- embryonic lethality, complete penetrance / MGI
- embryonic lethality during organogenesis, complete penetrance / MGI
- abnormal primitive endoderm morphology / MGI
- decreased somite size / MGI
- fused somites / MGI
- delayed heart development / MGI
- embryonic-extraembryonic boundary constriction / MGI
- rostral body truncation / MGI
- abnormal chordamesoderm morphology / MGI
- abnormal primitive streak elongation / MGI
- increased embryonic tissue cell apoptosis / MGI
C57BL/6J-Foxa2em1H/H
Status | Available to order |
EMMA ID | EM:15131 |
Citation information | RRID:IMSR_EM:15131 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6J-Foxa2em1H/H |
Alternative name | Foxa2-S169P-EM1-B6J |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Foxa2em1H |
Gene/Transgene symbol | Foxa2 |
Information from provider
Provider | MRC-Harwell |
Provider affiliation | Mary Lyon Centre at MRC Harwell |
Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
Breeding history | Co-isogenic on original background |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | not known |
Immunocompromised | not known |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Combined pituitary hormone deficiencies, genetic forms / Orphanet_95494
MGI phenotypes (gene matching)
Information on how we integrate external resources can be found here
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