B6;CBA-Tg(Hsp70-1-cre)1Arge/Flmg
| Status | Available to order |
| EMMA ID | EM:15068 |
| Citation information | RRID:IMSR_EM:15068 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;CBA-Tg(Hsp70-1-cre)1Arge/Flmg |
| Alternative name | Hs-cre1 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Hsp70-1-cre)1Arge |
| Gene/Transgene symbol | Tg(Hsp70-1-cre)1Arge |
Information from provider
| Provider | Argiris Efstratiadis |
| Provider affiliation | Biomedical Research Foundation, Academy of Athens (BRFAA) |
| Genetic information | The cre-producer mouse transgenic line Hs-cre1 expresses a cre recombinase transgene from a heat shock (Hsp70-1) gene promoter for a simple and rapid approach to ubiquitous conditional gene disruption. Hs-cre1 behaves predominantly as a 'deleter' strain, since the majority of progeny (approximately 70-85%) exhibit complete recombination, regardless of reporter locus. |
| Phenotypic information | Homozygous:NoneHeterozygous:None |
| Breeding history | Not known |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | B.S.R.C. Alexander Fleming, Vari, Greece |
Literature references
- Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes.;Dietrich P, Dragatsis I, Xuan S, Zeitlin S, Efstratiadis A, ;2000;Mammalian genome : official journal of the International Mammalian Genome Society;11;196-205; 10723724