C57BL/6NTac-Agtem1(IMPC)H/H

Status

Available to order

EMMA IDEM:14999
Citation informationRRID:IMSR_EM:14999 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NTac-Agtem1(IMPC)H/H
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolAgtem1(IMPC)H
Gene/Transgene symbolAgt

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • hydronephrosis / MGI
  • abnormal kidney cortex morphology / MGI
  • abnormal kidney blood vessel morphology / MGI
  • decreased body weight / MGI
  • decreased body size / MGI
  • hyperactivity / MGI
  • polydipsia / MGI
  • hypotension / MGI
  • polyuria / MGI
  • abnormal postnatal growth/weight/body size / MGI
  • abnormal kidney morphology / MGI
  • decreased circulating aldosterone level / MGI
  • dilated renal tubules / MGI
  • abnormal juxtaglomerular apparatus morphology / MGI
  • decreased heart weight / MGI
  • increased systemic arterial blood pressure / MGI
  • decreased systemic arterial blood pressure / MGI
  • decreased urine osmolality / MGI
  • renal interstitial fibrosis / MGI
  • increased circulating renin level / MGI
  • decreased ovulation rate / MGI
  • decreased liver weight / MGI
  • increased kidney weight / MGI
  • decreased renal glomerulus number / MGI
  • dilated kidney collecting duct / MGI
  • kidney atrophy / MGI
  • abnormal blood-brain barrier function / MGI
  • abnormal enzyme/coenzyme level / MGI
  • abnormal renal glomerulus morphology / MGI
  • renal/urinary system phenotype / MGI
  • cardiovascular system phenotype / MGI
  • reproductive system phenotype / MGI
  • vascular smooth muscle hyperplasia / MGI
  • abnormal renal/urinary system physiology / MGI
  • increased renal plasma flow rate / MGI
  • increased circulating creatinine level / MGI
  • abnormal renal filtration rate / MGI
  • decreased creatinine clearance / MGI
  • increased circulating antidiuretic hormone level / MGI
  • decreased urine potassium level / MGI
  • decreased systemic arterial diastolic blood pressure / MGI
  • decreased systemic arterial systolic blood pressure / MGI
  • decreased urine sodium level / MGI
  • increased circulating angiotensinogen level / MGI
  • decreased circulating angiotensinogen level / MGI
  • abnormal hippocampus granule cell layer / MGI
  • slow postnatal weight gain / MGI
  • decreased fat cell size / MGI
  • decreased epididymal fat pad weight / MGI
  • abnormal blood homeostasis / MGI
  • decreased total body fat amount / MGI
  • postnatal lethality, incomplete penetrance / MGI
  • kidney papillary atrophy / MGI
  • abnormal kidney afferent arteriole morphology / MGI
  • abnormal kidney cortex artery morphology / MGI
  • abnormal kidney interlobular artery morphology / MGI
  • abnormal kidney inner medulla morphology / MGI
  • renal tubule atrophy / MGI
  • expanded mesangial matrix / MGI
  • tubulointerstitial nephritis / MGI
  • kidney medulla atrophy / MGI
  • kidney cortex atrophy / MGI
  • increased urine flow rate / MGI
  • decreased urine aldosterone level / MGI
  • increased urine antidiuretic hormone level / MGI
  • kidney papillary hypoplasia / MGI
  • increased fluid intake / MGI

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
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Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

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