B6J.C3H-Crybb1m1Mhda/Ieg

Status

Available to order

EMMA IDEM:14978
International strain nameB6J.C3H-Crybb1m1Mhda/Ieg
Alternative nameCrybb1_Asp167
Strain typeInduced Mutant Strains : Chemically-induced
Allele/Transgene symbolCrybb1m1Mhda
Gene/Transgene symbolCrybb1

Information from provider

ProviderMartin Hrabé de Angelis
Provider affiliationInstitute of Experimental Genetics, Helmholtz Zentrum München
Genetic informationENU-induced mutation in Crybb1 gene: c500A>T; pAsp167Val

Disclaimer - Special restrictions:

1) Mutant development was phenotype driven. Although for some mutant lines, linkage data and the molecular characterization of the causative mutation has been published, EMMA has not genotyped the strains and can not provide genotyping protocols.
2) Some lines showed low penetrance of the phenotype.
3) Only sperm available. Rederivation service can not be offered.
4) EMMA quality control standards may not apply for these strains.
5) EMMA has not verified the breeding performance and the genetic background of the strains.

The genotype/phenotype of the mice is not confirmed by INFRAFRONTIER/EMMA. We strongly recommend that the recipient confirms genotype/phenotype upon receipt.
Phenotypic informationHomozygous:
The homozygous mice have a dominant cataract.

Heterozygous:
The heterozygous mice have healthy lenses.
Breeding historyMore than 12 backcrosses to C57BL/6J.
ReferencesNone available
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archivingheterozygous C57BL/6J

Disease and phenotype information

IMPC phenotypes (gene matching)
  • increased total retina thickness / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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