C57BL/6-Tmem233tm1.1(cre)Jcox/H
| Status | Available to order |
| EMMA ID | EM:14935 |
| International strain name | C57BL/6-Tmem233tm1.1(cre)Jcox/H |
| Alternative name | Tmem233 Cre |
| Strain type | Targeted Mutant Strains : Knock-in |
| Allele/Transgene symbol | Tmem233tm1.1(cre)Jcox |
| Gene/Transgene symbol | Tmem233 |
Information from provider
| Provider | James Cox |
| Provider affiliation | WIBR, UCL |
| Genetic information | The Tmem233 Cre line is a constitutive knock-in line in which the Kozak-Cre-pA cassette replaced the ATG start codon of the murine Tmem233 gene. The cre recombinase expression is under the control of Tmem233 regulatory elements with homozygotes being knock-outs of the Tmem233 gene. |
| Phenotypic information | Homozygous:Apparently normal (although female homozygotes have lower weights than wild-type female littermates).Heterozygous:Apparently normal. See phenotyping report. |
| Breeding history | Less than 5 backcrosses to C57BL/6J. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- Tools for analysis and conditional deletion of subsets of sensory neurons.;Santana-Varela Sonia, Bogdanov Yury D, Gossage Samuel J, Okorokov Andrei L, Li Shengnan, de Clauser Larissa, Alves-Simoes Marta, Sexton Jane E, Iseppon Federico, Luiz Ana P, Zhao Jing, Wood John N, Cox James J, ;2021;Wellcome open research;6;250; 35233469