C57BL/6-Tg(Tmem45b-cre)#Jcox/H
| Status | Available to order |
| EMMA ID | EM:14934 |
| International strain name | C57BL/6-Tg(Tmem45b-cre)#Jcox/H |
| Alternative name | Tmem45b Cre |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Tmem45b-cre)#Jcox |
| Gene/Transgene symbol | Tg(Tmem45b-cre)#Jcox |
Information from provider
| Provider | James Cox |
| Provider affiliation | WIBR, UCL |
| Genetic information | The Tmem45b Cre line is a BAC transgenic in which a fragment containing the Cre-SV40 pA together with Frt-kanamycin cassette-Frt was introduced in exon 2 of the murine Tmem45b gene within BAC clone RP24-249I6. The kanamycin cassette was removed from the recombinant BAC by flp-mediated recombination. The recombinant clone was verified by PCR and end-sequencing and then injected into fertilized eggs for transgenic mouse production. |
| Phenotypic information | Homozygous:Not knownHeterozygous:Apparently normal |
| Breeding history | Generated by Cyagen on a C57BL/6 background. Less than 5 backcrosses to C57BL/6J. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- Tools for analysis and conditional deletion of subsets of sensory neurons.;Santana-Varela Sonia, Bogdanov Yury D, Gossage Samuel J, Okorokov Andrei L, Li Shengnan, de Clauser Larissa, Alves-Simoes Marta, Sexton Jane E, Iseppon Federico, Luiz Ana P, Zhao Jing, Wood John N, Cox James J, ;2021;Wellcome open research;6;250; 35233469