C57BL/6NTac-Snap29tm1c(EUCOMM)Wtsi/Orl

Status

Available to order

EMMA IDEM:14931
International strain nameC57BL/6NTac-Snap29tm1c(EUCOMM)Wtsi/Orl
Alternative nameC57BL/6NTac-Snap29tm1c(EUCOMM)Wtsi/WtsiCnbc
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolSnap29tm1c(EUCOMM)Wtsi
Gene/Transgene symbolSnap29

Information from provider

ProviderCécile FREMOND
Provider affiliationCNRS-TAAM-CDTA-UAR44
Genetic informationThis mouse line originates from EUCOMM ES clone EPD0065_4_B10. For further details on the construction of this clone see the relevant page at the IMPC portal (https://www.mousephenotype.org/data/alleles/MGI:1914724/tm1a(EUCOMM)Wtsi). Rederived tm1a mice (EMMA strain EM:05226) have been crossed with flp recombinase-deleter mice (EMMA strain EM:05490, C57BL/6NTac-Gt(ROSA)26Sortm2(CAG-flpo,-EYFP)Ics/Ics) to obtain the tm1c allele.
Phenotypic informationHomozygous:
Homozygous mice have not been generated.

Heterozygous:
Nothing.
Breeding historyRederived tm1a mice (EMMA strain EM:05226) have been crossed with flp-deleter mice (EMMA strain EM:05490) to obtain the tm1c allele.
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreInstitut de Transgenose, INTRAGENE, Orléans, France
Animals used for archivingheterozygous C57BL/6NTac

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (gene matching)
  • extramedullary hemopoiesis / IMPC
  • hyperplasia / IMPC
  • increased body length / IMPC
  • increased lean body mass / IMPC
  • increased bone mineral content / IMPC
  • increased bone mineral density / IMPC
MGI phenotypes (gene matching)
  • increased bone mineral density / MGI
  • scaly skin / MGI
  • tight skin / MGI
  • hyperkeratosis / MGI
  • increased body weight / MGI
  • acanthosis / MGI
  • increased lean body mass / MGI
  • abnormal skin physiology / MGI
  • abnormal autophagy / MGI
  • abnormal epidermal lamellar body morphology / MGI
  • decreased birth body size / MGI
  • abnormal skin appearance / MGI
  • increased bone mineral content / MGI
  • abnormal endoplasmic reticulum physiology / MGI
  • increased endoplasmic reticulum stress / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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