C57BL/6N-A^tm1Brd Il1r2^{tm1c(EUCOMM)Wtsi}/WtsiPh

Status	Available to order
EMMA ID	EM:14887
Citation information	RRID:IMSR_EM:14887 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	C57BL/6N-A^tm1Brd Il1r2^{tm1c(EUCOMM)Wtsi}/WtsiPh
Alternative name	C57BL/6N-Atm1Brd Il1r2tm1c(EUCOMM)Wtsi/WtsiPh
Strain type	Targeted Mutant Strains : Conditional mutation
Allele/Transgene symbol	Il1r2^{tm1c(EUCOMM)Wtsi}
Gene/Transgene symbol	Il1r2

Information from provider

Provider	Jana Kopkanova
Provider affiliation	Institute of Molecular Genetics of the Czech Academy of Sciences
Genetic information	This mouse line originates from EUCOMM ES clone EPD0680_6_G10 (Il1r2 allele). For further details on the construction of this clone see the relevant page at the IMPC portal. For tm1a to tm1c allele conversion the B6N Gt(ROSA)26Sor-tm2(CAG-flpo,-EYFP)Ics/Ics flp deleter strain (EMMA ID EM:05490) was used.
Phenotypic information	Homozygous: not tested Heterozygous: without phenotype
Breeding history	2 backcrosses to C57BL/6NCrl.
References	None available
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	Institute of Molecular Genetics, Prague, Czech Republic
Animals used for archiving	heterozygous C57BL/6NCrl males

Disease and phenotype information

IMPC phenotypes (gene matching)

increased grip strength / IMPC
abnormal auditory brainstem response / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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C57BL/6N-Atm1Brd Il1r2tm1c(EUCOMM)Wtsi/WtsiPh