C57BL/6NCrl-Irag1em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:14870
Citation informationRRID:IMSR_EM:14870 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Irag1em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolIrag1em1(IMPC)Ccpcz
Gene/Transgene symbolIrag1

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (allele matching)
  • increased neutrophil cell number / IMPC
  • abnormal cecum morphology / IMPC
  • abnormal liver morphology / IMPC
  • enlarged liver / IMPC
  • abnormal spleen morphology / IMPC
  • enlarged spleen / IMPC
  • small seminal vesicle / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • increased mean corpuscular volume / IMPC
  • decreased hemoglobin content / IMPC
  • decreased erythrocyte cell number / IMPC
  • decreased lean body mass / IMPC
  • increased spleen weight / IMPC
  • increased eosinophil cell number / IMPC
  • decreased lymphocyte cell number / IMPC
  • increased mean corpuscular hemoglobin / IMPC
  • enlarged cecum / IMPC
  • increased total body fat amount / IMPC
  • increased red blood cell distribution width / IMPC
  • increased fasting circulating glucose level / IMPC
IMPC phenotypes (gene matching)
  • increased eosinophil cell number / IMPC
  • increased mean corpuscular volume / IMPC
  • abnormal spleen morphology / IMPC
  • enlarged cecum / IMPC
  • decreased lean body mass / IMPC
  • enlarged spleen / IMPC
  • abnormal cecum morphology / IMPC
  • increased red blood cell distribution width / IMPC
  • decreased erythrocyte cell number / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • increased fasting circulating glucose level / IMPC
  • increased spleen weight / IMPC
  • enlarged liver / IMPC
  • abnormal liver morphology / IMPC
  • increased neutrophil cell number / IMPC
  • small seminal vesicle / IMPC
  • decreased hemoglobin content / IMPC
  • increased mean corpuscular hemoglobin / IMPC
  • increased total body fat amount / IMPC
  • decreased lymphocyte cell number / IMPC

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

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    * In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

    More details on pricing and delivery times

    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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