IMPC phenotypes (allele matching)
C57BL/6NCrl-Il1r1em1(IMPC)Ccpcz/Ph
| Status | Under development - register interest |
| EMMA ID | EM:14858 |
| International strain name | C57BL/6NCrl-Il1r1em1(IMPC)Ccpcz/Ph |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Il1r1em1(IMPC)Ccpcz |
| Gene/Transgene symbol | Il1r1 |
Information from provider
| Provider | Institute of Molecular Genetics |
| Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased neutrophil cell number / MGI
- abnormal cell death / MGI
- increased body length / MGI
- increased body weight / MGI
- weight loss / MGI
- decreased anxiety-related response / MGI
- hypoactivity / MGI
- abnormal inflammatory response / MGI
- increased circulating insulin level / MGI
- no abnormal phenotype detected / MGI
- abnormal nervous system electrophysiology / MGI
- increased susceptibility to bacterial infection / MGI
- decreased immunoglobulin level / MGI
- abnormal neutrophil physiology / MGI
- enhanced wound healing / MGI
- increased growth rate / MGI
- increased liver weight / MGI
- delayed tooth eruption / MGI
- increased susceptibility to age related obesity / MGI
- decreased susceptibility to induced arthritis / MGI
- abnormal response/metabolism to endogenous compounds / MGI
- increased susceptibility to induced arthritis / MGI
- impaired febrile response / MGI
- abnormal lean body mass / MGI
- decreased susceptibility to kidney reperfusion injury / MGI
- decreased incidence of tumors by chemical induction / MGI
- increased circulating insulin-like growth factor I level / MGI
- decreased susceptibility to autoimmune diabetes / MGI
- decreased susceptibility to experimental autoimmune uveoretinitis / MGI
- abnormal vascular wound healing / MGI
- increased bone resorption / MGI
- decreased eosinophil cell number / MGI
- decreased T cell number / MGI
- sepsis / MGI
- decreased T cell proliferation / MGI
- osteomyelitis / MGI
- impaired glucose tolerance / MGI
- insulin resistance / MGI
- homeostasis/metabolism phenotype / MGI
- immune system phenotype / MGI
- abnormal food intake / MGI
- increased percent body fat/body weight / MGI
- decreased circulating creatinine level / MGI
- decreased blood urea nitrogen level / MGI
- decreased susceptibility to type IV hypersensitivity reaction / MGI
- increased circulating leptin level / MGI
- increased body mass index / MGI
- decreased tumor necrosis factor secretion / MGI
- decreased circulating interleukin-6 level / MGI
- increased circulating interleukin-18 level / MGI
- decreased circulating interleukin-18 level / MGI
- increased circulating interleukin-1 beta level / MGI
- decreased interleukin-6 secretion / MGI
- impaired neutrophil chemotaxis / MGI
- decreased transforming growth factor level / MGI
- increased gonadal fat pad weight / MGI
- increased abdominal fat pad weight / MGI
- increased inguinal fat pad weight / MGI
- increased mesenteric fat pad weight / MGI
- increased retroperitoneal fat pad weight / MGI
- enhanced contextual conditioning behavior / MGI
- increased susceptibility to bacterial infection induced morbidity/mortality / MGI
- increased total body fat amount / MGI
- abnormal circulating serum amyloid protein level / MGI
- increased respiratory quotient / MGI
- abnormal microglial cell activation / MGI
- integument phenotype / MGI
- dental pulp necrosis / MGI