- abnormal rib morphology / MGI
- abnormal sternum morphology / MGI
- absent kidney / MGI
- cortical renal glomerulopathies / MGI
- abnormal kidney development / MGI
- delayed kidney development / MGI
- syndactyly / MGI
- clubfoot / MGI
- abnormal lung morphology / MGI
- abnormal lung development / MGI
- blistering / MGI
- microphthalmia / MGI
- eyelids open at birth / MGI
- hemorrhage / MGI
- abnormal hair growth / MGI
- abnormal eye morphology / MGI
- abnormal digit morphology / MGI
- micrognathia / MGI
- small kidney / MGI
- no phenotypic analysis / MGI
- single kidney / MGI
- kidney cysts / MGI
- abnormal lung vasculature morphology / MGI
- abnormal basement membrane morphology / MGI
- abnormal sternebra morphology / MGI
- impaired branching involved in ureteric bud morphogenesis / MGI
- cryptophthalmos / MGI
- glomerulosclerosis / MGI
- narrow eye opening / MGI
- abnormal renal glomerulus morphology / MGI
- renal/urinary system phenotype / MGI
- craniofacial phenotype / MGI
- abnormal ureteric bud morphology / MGI
- abnormal lung epithelium morphology / MGI
- bleb / MGI
- fetal bleb / MGI
- abnormal secondary palate development / MGI
- preaxial polydactyly / MGI
- abnormal palatal shelf fusion at midline / MGI
- cleft secondary palate / MGI
- perimembraneous ventricular septal defect / MGI
- integument phenotype / MGI
- fused right lung lobes / MGI
- abnormal metanephric mesenchyme morphology / MGI
- lethality throughout fetal growth and development, complete penetrance / MGI
- prenatal lethality, incomplete penetrance / MGI
- lethality throughout fetal growth and development, incomplete penetrance / MGI
- abnormal glomerular capillary morphology / MGI
- abnormal glomerular mesangium morphology / MGI
- abnormal metanephros morphology / MGI
- increased metanephric mesenchyme apoptosis / MGI
- abnormal glomerular capsule space morphology / MGI
C57BL/6NCrl-Fras1em1(IMPC)Ccpcz/Ph
Status | Under development - register interest |
EMMA ID | EM:14855 |
International strain name | C57BL/6NCrl-Fras1em1(IMPC)Ccpcz/Ph |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Fras1em1(IMPC)Ccpcz |
Gene/Transgene symbol | Fras1 |
Information from provider
Provider | Institute of Molecular Genetics |
Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Renal agenesis, unilateral / Orphanet_93100
- Fraser syndrome / Orphanet_2052
MGI phenotypes (gene matching)
Information on how we integrate external resources can be found here
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