C57BL/6NCrl-Fras1em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:14855
International strain nameC57BL/6NCrl-Fras1em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolFras1em1(IMPC)Ccpcz
Gene/Transgene symbolFras1

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • abnormal rib morphology / MGI
  • abnormal sternum morphology / MGI
  • absent kidney / MGI
  • cortical renal glomerulopathies / MGI
  • abnormal kidney development / MGI
  • delayed kidney development / MGI
  • syndactyly / MGI
  • clubfoot / MGI
  • abnormal lung morphology / MGI
  • abnormal lung development / MGI
  • blistering / MGI
  • microphthalmia / MGI
  • eyelids open at birth / MGI
  • hemorrhage / MGI
  • abnormal hair growth / MGI
  • abnormal eye morphology / MGI
  • abnormal digit morphology / MGI
  • micrognathia / MGI
  • small kidney / MGI
  • no phenotypic analysis / MGI
  • single kidney / MGI
  • kidney cysts / MGI
  • abnormal lung vasculature morphology / MGI
  • abnormal basement membrane morphology / MGI
  • abnormal sternebra morphology / MGI
  • impaired branching involved in ureteric bud morphogenesis / MGI
  • cryptophthalmos / MGI
  • glomerulosclerosis / MGI
  • narrow eye opening / MGI
  • abnormal renal glomerulus morphology / MGI
  • renal/urinary system phenotype / MGI
  • craniofacial phenotype / MGI
  • abnormal ureteric bud morphology / MGI
  • abnormal lung epithelium morphology / MGI
  • bleb / MGI
  • fetal bleb / MGI
  • abnormal secondary palate development / MGI
  • preaxial polydactyly / MGI
  • abnormal palatal shelf fusion at midline / MGI
  • cleft secondary palate / MGI
  • perimembraneous ventricular septal defect / MGI
  • integument phenotype / MGI
  • fused right lung lobes / MGI
  • abnormal metanephric mesenchyme morphology / MGI
  • lethality throughout fetal growth and development, complete penetrance / MGI
  • prenatal lethality, incomplete penetrance / MGI
  • lethality throughout fetal growth and development, incomplete penetrance / MGI
  • abnormal glomerular capillary morphology / MGI
  • abnormal glomerular mesangium morphology / MGI
  • abnormal metanephros morphology / MGI
  • increased metanephric mesenchyme apoptosis / MGI
  • abnormal glomerular capsule space morphology / MGI

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

    Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

    * In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

    More details on pricing and delivery times

    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

    Other EMMA strains

    Not found what you were looking for? Search here for other strains available from EMMA.


    Search
    INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).