C57BL/6NCrl-Wnt7aem1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:14852
Citation informationRRID:IMSR_EM:14852 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Wnt7aem1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolWnt7aem1(IMPC)Ccpcz
Gene/Transgene symbolWnt7a

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • decreased presacral vertebrae number / MGI
  • increased rib number / MGI
  • abnormal forelimb morphology / MGI
  • abnormal hindlimb morphology / MGI
  • polydactyly / MGI
  • oligodactyly / MGI
  • abnormal uterus morphology / MGI
  • abnormal gait / MGI
  • limb grasping / MGI
  • infertility / MGI
  • male infertility / MGI
  • female infertility / MGI
  • abnormal limb morphology / MGI
  • abnormal digit morphology / MGI
  • no abnormal phenotype detected / MGI
  • small uterus / MGI
  • abnormal sperm motility / MGI
  • short fibula / MGI
  • abnormal uterus development / MGI
  • abnormal oviduct morphology / MGI
  • abnormal Mullerian duct morphology / MGI
  • scapular bone foramen / MGI
  • short humerus / MGI
  • absent ulna / MGI
  • abnormal ulna morphology / MGI
  • abnormal humerus morphology / MGI
  • hearing/vestibular/ear phenotype / MGI
  • reproductive system phenotype / MGI
  • skeleton phenotype / MGI
  • vision/eye phenotype / MGI
  • abnormal limb development / MGI
  • thin myometrium / MGI
  • fused phalanges / MGI
  • hemimelia / MGI
  • short oviduct / MGI
  • thin uterus / MGI
  • absent endometrial glands / MGI
  • failure of Mullerian duct regression / MGI
  • abnormal skin appearance / MGI
  • prenatal lethality, incomplete penetrance / MGI

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

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    * In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

    More details on pricing and delivery times

    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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