C57BL/6NCrl-Dcaf5em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:14773
Citation informationRRID:IMSR_EM:14773 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Dcaf5em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolDcaf5em1(IMPC)Ccpcz
Gene/Transgene symbolDcaf5

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (allele matching)
  • abnormal heart morphology / IMPC
  • enlarged heart / IMPC
  • abnormal spleen morphology / IMPC
  • enlarged spleen / IMPC
  • small spleen / IMPC
  • enlarged lymph nodes / IMPC
  • decreased body weight / IMPC
  • abnormal retina morphology / IMPC
  • hyperactivity / IMPC
  • decreased locomotor activity / IMPC
  • decreased exploration in new environment / IMPC
  • abnormal tooth morphology / IMPC
  • abnormal lymph node morphology / IMPC
  • short tibia / IMPC
  • decreased circulating alkaline phosphatase level / IMPC
  • increased spleen weight / IMPC
  • increased NK cell number / IMPC
  • increased effector memory CD8-positive, alpha-beta T cell number / IMPC
  • increased lung elastance / IMPC
IMPC phenotypes (gene matching)
  • decreased body weight / IMPC
  • enlarged spleen / IMPC
  • abnormal spleen morphology / IMPC
  • abnormal retina morphology / IMPC
  • increased lung elastance / IMPC
  • decreased exploration in new environment / IMPC
  • hyperactivity / IMPC
  • abnormal heart morphology / IMPC
  • abnormal lymph node morphology / IMPC
  • enlarged heart / IMPC
  • small spleen / IMPC
  • short tibia / IMPC
  • abnormal tooth morphology / IMPC
  • increased spleen weight / IMPC
  • enlarged lymph nodes / IMPC
  • increased NK cell number / IMPC
  • decreased locomotor activity / IMPC
  • decreased circulating alkaline phosphatase level / IMPC
  • increased effector memory CD8-positive, alpha-beta T cell number / IMPC

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Other EMMA strains

Not found what you were looking for? Search here for other strains available from EMMA.


Search
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).