C57BL/6NTac-Hoxb4em1(IMPC)H/H

Status

Available to order

EMMA IDEM:14757
International strain nameC57BL/6NTac-Hoxb4em1(IMPC)H/H
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolHoxb4em1(IMPC)H
Gene/Transgene symbolHoxb4

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (gene matching)
  • abnormal sternum morphology / MGI
  • abnormal heart morphology / MGI
  • thin ventricular wall / MGI
  • decreased bone marrow cell number / MGI
  • spleen hypoplasia / MGI
  • decreased body size / MGI
  • edema / MGI
  • respiratory distress / MGI
  • abnormal definitive hematopoiesis / MGI
  • no abnormal phenotype detected / MGI
  • decreased hemoglobin content / MGI
  • decreased erythrocyte cell number / MGI
  • abnormal cervical vertebrae morphology / MGI
  • abnormal abdominal wall morphology / MGI
  • abnormal ventral body wall morphology / MGI
  • abnormal body wall morphology / MGI
  • absent pericardium / MGI
  • pallor / MGI
  • diaphragmatic hernia / MGI
  • abnormal chest morphology / MGI
  • split sternum / MGI
  • abnormal sternebra morphology / MGI
  • abnormal cervical axis morphology / MGI
  • cervical vertebral transformation / MGI
  • muscle phenotype / MGI
  • growth/size/body region phenotype / MGI
  • skeleton phenotype / MGI
  • abnormal heart position or orientation / MGI
  • dilated heart ventricle / MGI
  • decreased survivor rate / MGI
  • thin interventricular septum / MGI
  • mortality/aging / MGI
  • neonatal lethality, complete penetrance / MGI
  • neonatal lethality, incomplete penetrance / MGI
  • prenatal lethality, incomplete penetrance / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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