C57BL/6NTac-Tacr1em2H/H

Status

Available to order

EMMA IDEM:14655
Citation informationRRID:IMSR_EM:14655 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NTac-Tacr1em2H/H
Alternative nameTACR1-R244C-EM2-B6N
Strain typeEndonuclease-mediated
Allele/Transgene symbolTacr1em2H
Gene/Transgene symbolTacr1

Information from provider

Provider MRC-Harwell
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationFor detailed information on the genetic description of this strain, please have a look at this report.
Phenotypic informationHomozygous:
not known

Heterozygous:
None reported
Breeding historyCo-isogenic on original background
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (gene matching)
  • decreased anxiety-related response / MGI
  • hyperactivity / MGI
  • impaired coordination / MGI
  • abnormal body temperature homeostasis / MGI
  • abnormal humoral immune response / MGI
  • decreased inflammatory response / MGI
  • abnormal dopamine level / MGI
  • increased airway responsiveness / MGI
  • abnormal touch/ nociception / MGI
  • abnormal pain threshold / MGI
  • abnormal nervous system electrophysiology / MGI
  • abnormal respiratory mucosa goblet cell morphology / MGI
  • abnormal mast cell physiology / MGI
  • decreased circulating corticosterone level / MGI
  • abnormal chemical nociception / MGI
  • abnormal nociception after inflammation / MGI
  • joint inflammation / MGI
  • decreased vascular permeability / MGI
  • decreased nerve fiber response intensity / MGI
  • abnormal nervous system physiology / MGI
  • abnormal thermosensation / MGI
  • abnormal noradrenaline level / MGI
  • abnormal neuron physiology / MGI
  • hyperalgesia / MGI
  • hyporesponsive to tactile stimuli / MGI
  • decreased aggression / MGI
  • increased chemical nociceptive threshold / MGI
  • abnormal physiological response to xenobiotic / MGI
  • impaired conditioned place preference behavior / MGI
  • impaired behavioral response to xenobiotic / MGI
  • impaired behavioral response to addictive substance / MGI
  • impaired behavioral response to morphine / MGI
  • decreased vocalization / MGI
  • abnormal pulmonary respiratory rate response / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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