IMPC phenotypes (gene matching)
C57BL/6J-Syt1em1H/H
| Status | Available to order |
| EMMA ID | EM:14653 |
| Citation information | RRID:IMSR_EM:14653 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6J-Syt1em1H/H |
| Alternative name | SYT1-F349A-EM1-B6 |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Syt1em1H |
| Gene/Transgene symbol | Syt1 |
Information from provider
| Provider | MRC-Harwell |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
| Phenotypic information | Homozygous:not knownHeterozygous:None reported |
| Breeding history | Co-isogenic on original background |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Infantile hypotonia-oculomotor anomalies-hyperkinetic movements-developmental delay syndrome / Orphanet_522077
MGI phenotypes (gene matching)
- abnormal suckling behavior / MGI
- no abnormal phenotype detected / MGI
- abnormal CNS synaptic transmission / MGI
- abnormal adrenal gland physiology / MGI
- abnormal excitatory postsynaptic currents / MGI
- increased synaptic depression / MGI
- abnormal inhibitory postsynaptic currents / MGI
- dilated bile duct / MGI
- biliary cyst / MGI
- nervous system phenotype / MGI
- abnormal synaptic transmission / MGI
- abnormal miniature excitatory postsynaptic currents / MGI
- abnormal neuron physiology / MGI
- abnormal neurotransmitter secretion / MGI
- thoracoschisis / MGI
- perimembraneous ventricular septal defect / MGI
- postnatal lethality, complete penetrance / MGI
- adrenal gland cyst / MGI
- thyroid cyst / MGI
- abnormal ductus venosus valve morphology / MGI
- abnormal infrahyoid muscle connection / MGI
- abnormal coronary sinus connection / MGI