C57BL/6NTac-Stat2em1H/H

Status

Available to order

EMMA IDEM:14652
International strain nameC57BL/6NTac-Stat2em1H/H
Alternative nameSTAT2-FLOX-EM1-B6N
Strain typeEndonuclease-mediated
Allele/Transgene symbolStat2em1H
Gene/Transgene symbolStat2

Information from provider

Provider MRC-Harwell
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationFor detailed information on the genetic description of this strain, please have a look at this report.
Phenotypic informationHomozygous:
not known

Heterozygous:
None reported
Breeding historyCo-isogenic on original background
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

    • Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection / Orphanet_431166
MGI phenotypes (gene matching)
  • decreased level of surface class I molecules / MGI
  • abnormal T cell differentiation / MGI
  • increased susceptibility to viral infection / MGI
  • abnormal level of surface class II molecules / MGI
  • decreased CD8-positive, alpha-beta T cell number / MGI
  • decreased single-positive T cell number / MGI
  • decreased plasmacytoid dendritic cell number / MGI
  • decreased dendritic cell number / MGI
  • increased susceptibility to viral infection induced morbidity/mortality / MGI
  • decreased central memory CD8 positive, alpha-beta T cell number / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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