C57BL/6J-Polgem1H/H
| Status | Available to order |
| EMMA ID | EM:14641 |
| International strain name | C57BL/6J-Polgem1H/H |
| Alternative name | POLG-A449T-EM1-B6 |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Polgem1H |
| Gene/Transgene symbol | Polg |
Information from provider
| Provider | MRC-Harwell |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
| Phenotypic information | Homozygous:not knownHeterozygous:None reported |
| Breeding history | Co-isogenic on original background |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Alpers-Huttenlocher syndrome / Orphanet_726
- Spinocerebellar ataxia with epilepsy / Orphanet_254881
- Autosomal dominant progressive external ophthalmoplegia / Orphanet_254892
- Mitochondrial neurogastrointestinal encephalomyopathy / Orphanet_298
- Recessive mitochondrial ataxia syndrome / Orphanet_94125
- Sensory ataxic neuropathy-dysarthria-ophthalmoparesis syndrome / Orphanet_70595
- Autosomal recessive progressive external ophthalmoplegia / Orphanet_254886