IMPC phenotypes (gene matching)
C57BL/6J-Cd1d1em1H/H
| Status | Available to order |
| EMMA ID | EM:14616 |
| International strain name | C57BL/6J-Cd1d1em1H/H |
| Alternative name | CD1D1-LPETG-EM1-B6 |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Cd1d1em1H |
| Gene/Transgene symbol | Cd1d1 |
Information from provider
| Provider | MRC-Harwell |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
| Phenotypic information | Homozygous:not knownHeterozygous:None reported |
| Breeding history | Co-isogenic on original background |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal liver morphology / MGI
- decreased IgG level / MGI
- arrested T cell differentiation / MGI
- abnormal T cell activation / MGI
- abnormal antigen presentation / MGI
- autoimmune response / MGI
- kidney inflammation / MGI
- lung inflammation / MGI
- increased susceptibility to bacterial infection / MGI
- abnormal dendritic cell antigen presentation / MGI
- glomerulonephritis / MGI
- increased urine protein level / MGI
- increased susceptibility to ischemic brain injury / MGI
- renal interstitial fibrosis / MGI
- decreased susceptibility to induced arthritis / MGI
- increased anti-double stranded DNA antibody level / MGI
- increased anti-nuclear antigen antibody level / MGI
- decreased regulatory T cell number / MGI
- decreased acute inflammation / MGI
- glomerulosclerosis / MGI
- increased blood urea nitrogen level / MGI
- abnormal NK T cell morphology / MGI
- decreased NK T cell number / MGI
- abnormal NK T cell physiology / MGI
- abnormal CD4-positive T cell differentiation / MGI
- increased IgG3 level / MGI
- decreased tumor necrosis factor secretion / MGI
- decreased interferon-gamma secretion / MGI
- decreased interleukin-2 secretion / MGI
- abnormal interleukin-4 secretion / MGI
- decreased interleukin-4 secretion / MGI
- decreased physiological sensitivity to xenobiotic / MGI
- increased susceptibility to bacterial infection induced morbidity/mortality / MGI
- renal tubule atrophy / MGI
- glomerular crescent / MGI