- abnormal vertebrae morphology / MGI
- abnormal rib morphology / MGI
- rib bifurcation / MGI
- rib fusion / MGI
- kinked tail / MGI
- short tail / MGI
- fused dorsal root ganglion / MGI
- abnormal female reproductive system morphology / MGI
- abnormal oocyte morphology / MGI
- small ovary / MGI
- impaired ovarian folliculogenesis / MGI
- abnormal ovarian folliculogenesis / MGI
- abnormal ovarian follicle morphology / MGI
- abnormal lung development / MGI
- decreased body length / MGI
- decreased caudal vertebrae number / MGI
- abnormal embryo development / MGI
- abnormal somite development / MGI
- reduced fertility / MGI
- male infertility / MGI
- female infertility / MGI
- abnormal gametogenesis / MGI
- postnatal lethality / MGI
- abnormal axial skeleton morphology / MGI
- abnormal pulmonary alveolus morphology / MGI
- abnormal retinal vasculature morphology / MGI
- abnormal rib development / MGI
- no phenotypic analysis / MGI
- abnormal thoracic vertebrae morphology / MGI
- abnormal lumbar vertebrae morphology / MGI
- abnormal sacral vertebrae morphology / MGI
- decreased rib number / MGI
- abnormal embryonic hematopoiesis / MGI
- abnormal lung vasculature morphology / MGI
- caudal body truncation / MGI
- vertebral fusion / MGI
- abnormal thoracic cage morphology / MGI
- decreased cervical vertebrae number / MGI
- absent caudal vertebrae / MGI
- abnormal female meiosis / MGI
- abnormal rostral-caudal axis patterning / MGI
- abnormal somite size / MGI
- abnormal dorsal-ventral polarity of the somites / MGI
- abnormal vertebrae development / MGI
- abnormal vertebral body development / MGI
- hearing/vestibular/ear phenotype / MGI
- embryo phenotype / MGI
- skeleton phenotype / MGI
- impaired lung alveolus development / MGI
- abnormal sclerotome morphology / MGI
- abnormal sternocostal joint morphology / MGI
- abnormal costovertebral joint morphology / MGI
- abnormal rostral-caudal patterning of the somites / MGI
- decreased survivor rate / MGI
- mortality/aging / MGI
- postnatal lethality, incomplete penetrance / MGI
- neonatal lethality, complete penetrance / MGI
- prenatal lethality, incomplete penetrance / MGI
- embryonic lethality, incomplete penetrance / MGI
- preweaning lethality, incomplete penetrance / MGI
C57BL/6N-Lfngem1(IMPC)Wtsi/WtsiCnbc
Status | Available to order |
EMMA ID | EM:14574 |
International strain name | C57BL/6N-Lfngem1(IMPC)Wtsi/WtsiCnbc |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Lfngem1(IMPC)Wtsi |
Gene/Transgene symbol | Lfng |
Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
Animals used for archiving | heterozygous C57BL/6N |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal recessive spondylocostal dysostosis / Orphanet_2311
MGI phenotypes (gene matching)
Information on how we integrate external resources can be found here
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