C57BL/6N-Lfngem1(IMPC)Wtsi/WtsiCnbc

Status

Available to order

EMMA IDEM:14574
Citation informationRRID:IMSR_EM:14574 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6N-Lfngem1(IMPC)Wtsi/WtsiCnbc
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolLfngem1(IMPC)Wtsi
Gene/Transgene symbolLfng

Information from provider

Provider Wellcome Trust Sanger Institute
Provider affiliationWellcome Trust Sanger Institute
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreCNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain
Animals used for archivingheterozygous C57BL/6N males

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • abnormal vertebrae morphology / MGI
  • abnormal rib morphology / MGI
  • rib bifurcation / MGI
  • rib fusion / MGI
  • kinked tail / MGI
  • short tail / MGI
  • fused dorsal root ganglion / MGI
  • abnormal female reproductive system morphology / MGI
  • abnormal oocyte morphology / MGI
  • small ovary / MGI
  • impaired ovarian folliculogenesis / MGI
  • abnormal ovarian folliculogenesis / MGI
  • abnormal ovarian follicle morphology / MGI
  • abnormal lung development / MGI
  • decreased body length / MGI
  • decreased caudal vertebrae number / MGI
  • abnormal embryo development / MGI
  • abnormal somite development / MGI
  • reduced fertility / MGI
  • male infertility / MGI
  • female infertility / MGI
  • abnormal gametogenesis / MGI
  • postnatal lethality / MGI
  • abnormal axial skeleton morphology / MGI
  • abnormal pulmonary alveolus morphology / MGI
  • abnormal retinal vasculature morphology / MGI
  • abnormal rib development / MGI
  • no phenotypic analysis / MGI
  • abnormal thoracic vertebrae morphology / MGI
  • abnormal lumbar vertebrae morphology / MGI
  • abnormal sacral vertebrae morphology / MGI
  • decreased rib number / MGI
  • abnormal embryonic hematopoiesis / MGI
  • abnormal lung vasculature morphology / MGI
  • caudal body truncation / MGI
  • vertebral fusion / MGI
  • abnormal thoracic cage morphology / MGI
  • decreased cervical vertebrae number / MGI
  • absent caudal vertebrae / MGI
  • abnormal female meiosis / MGI
  • abnormal rostral-caudal axis patterning / MGI
  • abnormal somite size / MGI
  • abnormal dorsal-ventral polarity of the somites / MGI
  • abnormal vertebrae development / MGI
  • abnormal vertebral body development / MGI
  • hearing/vestibular/ear phenotype / MGI
  • embryo phenotype / MGI
  • skeleton phenotype / MGI
  • impaired lung alveolus development / MGI
  • abnormal sclerotome morphology / MGI
  • abnormal sternocostal joint morphology / MGI
  • abnormal costovertebral joint morphology / MGI
  • abnormal rostral-caudal patterning of the somites / MGI
  • decreased survivor rate / MGI
  • mortality/aging / MGI
  • postnatal lethality, incomplete penetrance / MGI
  • neonatal lethality, complete penetrance / MGI
  • prenatal lethality, incomplete penetrance / MGI
  • embryonic lethality, incomplete penetrance / MGI
  • preweaning lethality, incomplete penetrance / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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