IMPC phenotypes (allele matching)
C57BL/6N-Pdzk1tm2b(EUCOMM)Wtsi/WtsiOulu
| Status | Available to order |
| EMMA ID | EM:14527 |
| International strain name | C57BL/6N-Pdzk1tm2b(EUCOMM)Wtsi/WtsiOulu |
| Alternative name | BEPD0005_1_D09 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Pdzk1tm2b(EUCOMM)Wtsi |
| Gene/Transgene symbol | Pdzk1 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
|
Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from EUCOMM ES clone BEPD0005_1_D09. For further details on the construction of this clone see the page at the IMPC portal. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele using a cell permeable HTN-Cre as described in doi:10.1007/s11248-013-9764-x. Click here for more information on EUCOMM final vectors. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | University of Oulu, Oulu, Finland |
Disease and phenotype information
MGI phenotypes (allele matching)
- polydactyly / MGI
- abnormal forebrain morphology / MGI
- abnormal lymphatic vessel morphology / MGI
- abnormal eye muscle morphology / MGI
- abnormal Mullerian duct morphology / MGI
- abnormal Wolffian duct morphology / MGI
- fusion of vertebral arches / MGI
- ostium primum atrial septal defect / MGI
- atrioventricular septal defect / MGI
- anomalous pulmonary venous connection / MGI
- absent segment of posterior cerebral artery / MGI
- subcutaneous edema / MGI
- abnormal vitelline vein connection / MGI
- abnormal infrahyoid muscle connection / MGI
- absent connection between subcutaneous lymph vessels and lymph sac / MGI
- blood in lymph vessels / MGI
- symmetric azygos veins / MGI
- double lumen aortic arch / MGI
- abnormal vertebral artery topology / MGI
MGI phenotypes (gene matching)
- polydactyly / MGI
- abnormal liver morphology / MGI
- abnormal forebrain morphology / MGI
- abnormal lymphatic vessel morphology / MGI
- abnormal eye muscle morphology / MGI
- abnormal Mullerian duct morphology / MGI
- abnormal Wolffian duct morphology / MGI
- fusion of vertebral arches / MGI
- increased circulating cholesterol level / MGI
- abnormal circulating protein level / MGI
- ostium primum atrial septal defect / MGI
- atrioventricular septal defect / MGI
- anomalous pulmonary venous connection / MGI
- absent segment of posterior cerebral artery / MGI
- subcutaneous edema / MGI
- abnormal vitelline vein connection / MGI
- abnormal infrahyoid muscle connection / MGI
- absent connection between subcutaneous lymph vessels and lymph sac / MGI
- blood in lymph vessels / MGI
- symmetric azygos veins / MGI
- double lumen aortic arch / MGI
- abnormal vertebral artery topology / MGI