IMPC phenotypes (allele matching)
C57BL/6N-Irf6em1(IMPC)Wtsi/WtsiCnbc
| Status | Available to order |
| EMMA ID | EM:14435 |
| Citation information | RRID:IMSR_EM:14435 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Irf6em1(IMPC)Wtsi/WtsiCnbc |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Irf6em1(IMPC)Wtsi |
| Gene/Transgene symbol | Irf6 |
Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | heterozygous C57BL/6N males |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal dominant popliteal pterygium syndrome / Orphanet_1300
- Oligodontia / Orphanet_99798
- Van der Woude syndrome / Orphanet_888
MGI phenotypes (gene matching)
- delayed bone ossification / MGI
- cleft palate / MGI
- abnormal tooth development / MGI
- decreased hair follicle number / MGI
- abnormal cranium morphology / MGI
- short snout / MGI
- abnormal mouth morphology / MGI
- abnormal jaw morphology / MGI
- abnormal esophagus morphology / MGI
- short limbs / MGI
- abnormal forelimb morphology / MGI
- abnormal hindlimb morphology / MGI
- syndactyly / MGI
- synostosis / MGI
- short tail / MGI
- abnormal tongue morphology / MGI
- shiny skin / MGI
- tight skin / MGI
- abnormal epidermal layer morphology / MGI
- thick epidermis / MGI
- abnormal epidermis stratum basale morphology / MGI
- abnormal epidermis suprabasal layer morphology / MGI
- abnormal epidermis stratum spinosum morphology / MGI
- absent epidermis stratum corneum / MGI
- absent vibrissae / MGI
- abnormal digit morphology / MGI
- abnormal craniofacial bone morphology / MGI
- abnormal keratinocyte morphology / MGI
- abnormal keratinocyte differentiation / MGI
- curly tail / MGI
- abnormal esophagus development / MGI
- abnormal craniofacial development / MGI
- abnormal skin development / MGI
- short sternum / MGI
- absent presphenoid bone / MGI
- abnormal palatine bone horizontal plate morphology / MGI
- small mandible / MGI
- abnormal mandibular angle morphology / MGI
- small vertebrae / MGI
- split xiphoid process / MGI
- decreased length of long bones / MGI
- abnormal phalanx morphology / MGI
- abnormal incisor morphology / MGI
- craniofacial phenotype / MGI
- abnormal skeleton morphology / MGI
- absent outer ear / MGI
- abnormal digit development / MGI
- fused phalanges / MGI
- delayed skin barrier formation / MGI
- absent epidermis stratum granulosum / MGI
- increased keratinocyte proliferation / MGI
- abnormal palate development / MGI
- palatal shelf fusion with tongue or mandible / MGI
- failure of palatal shelf elevation / MGI
- cleft secondary palate / MGI
- postnatal lethality, complete penetrance / MGI
- neonatal lethality, incomplete penetrance / MGI
- perinatal lethality, complete penetrance / MGI
- abnormal periderm development / MGI
- abnormal oral cavity morphology / MGI
- round snout / MGI