STOCK Mst1tm1(KOMP)Wtsi/WtsiH

Status

Only small colony available

EMMA IDEM:14384
International strain nameSTOCK Mst1tm1(KOMP)Wtsi/WtsiH
Alternative nameEPD0468_4_B11
Strain type
Allele/Transgene symbolMst1tm1(KOMP)Wtsi
Gene/Transgene symbolMst1
DisclaimerPlease note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
  1. We can not guarantee a null mutation for Knock-out first alleles (tm1a alleles, see http://www.mousephenotype.org/about-ikmc/targeting-strategies) as the critical exon has not been deleted.
  2. That the structure of the targeted mutation in the ES cells obtained from EUCOMM/KOMP to generate EUCOMM/KOMP mice is not verified by INFRAFRONTIER/EMMA. It is recommended that the recipient confirms the mutation structure.
  3. No check for determining the copy number of the targeting construct in ES cells obtained from EUCOMM/KOMP is done by INFRAFRONTIER/EMMA.
  4. The level of quality control before mice are released is to confirm the individual mouse genotype by short range PCR.

Information from provider

Provider Wellcome Trust Sanger Institute
Provider affiliationWellcome Trust Sanger Institute
Genetic informationThis mouse line originates from KOMP ES clone EPD0468_4_B11. For further details on the construction of this clone see the page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (allele matching)
  • increased mean corpuscular hemoglobin / MGI
MGI phenotypes (gene matching)
  • abnormal hepatocyte morphology / MGI
  • abnormal macrophage physiology / MGI
  • liver/biliary system phenotype / MGI
  • growth/size/body region phenotype / MGI
  • digestive/alimentary phenotype / MGI
  • immune system phenotype / MGI
  • hematopoietic system phenotype / MGI
  • increased mean corpuscular hemoglobin / MGI
  • increased susceptibility to induced colitis / MGI

Information on how we integrate external resources can be found here

Order (limited)

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

    Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

    * In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

    More details on pricing and delivery times

    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    MTA will be issued after an order has been submitted.

    EMMA conditions
    Legally binding conditions for the transfer

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