IMPC phenotypes (allele matching)
- preweaning lethality, complete penetrance / IMPC
C57BL/6N-Npattm1b(EUCOMM)Wtsi/WtsiIeg
| Status | Available to order |
| EMMA ID | EM:14323 |
| International strain name | C57BL/6N-Npattm1b(EUCOMM)Wtsi/WtsiIeg |
| Alternative name | EPD0370_4_H05 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Npattm1b(EUCOMM)Wtsi |
| Gene/Transgene symbol | Npat |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from EUCOMM ES clone EPD0370_4_H05. For further details on the construction of this clone see the page at the IMPC portal. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele using a cell permeable HTN-Cre as described in doi:10.1007/s11248-013-9764-x. Click here for more information on EUCOMM final vectors. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
IMPC phenotypes (gene matching)
- preweaning lethality, complete penetrance / IMPC
MGI phenotypes (allele matching)
- rib fusion / MGI
- abnormal interatrial septum morphology / MGI
- double outlet right ventricle / MGI
- abnormal atrioventricular cushion morphology / MGI
- abnormal adrenal gland morphology / MGI
- small superior cervical ganglion / MGI
- abnormal testis morphology / MGI
- abnormal Mullerian duct morphology / MGI
- fetal growth retardation / MGI
- fusion of vertebral arches / MGI
- abnormal humerus morphology / MGI
- thoracoschisis / MGI
- perimembraneous ventricular septal defect / MGI
- double ureter / MGI
- abnormal digastric muscle morphology / MGI
- subcutaneous edema / MGI
- abnormal ductus venosus valve morphology / MGI
- abnormal ureter topology / MGI
- abnormal infrahyoid muscle morphology / MGI
- multiple persisting craniopharyngeal ducts / MGI
- reduced sympathetic cervical ganglion size / MGI
- blood in lymph vessels / MGI
- symmetric azygos veins / MGI
- abnormal vertebral artery origin / MGI
- abnormal vertebral artery topology / MGI
- abnormal intestine placement / MGI
MGI phenotypes (gene matching)
- rib fusion / MGI
- abnormal interatrial septum morphology / MGI
- double outlet right ventricle / MGI
- abnormal atrioventricular cushion morphology / MGI
- abnormal adrenal gland morphology / MGI
- small superior cervical ganglion / MGI
- abnormal testis morphology / MGI
- abnormal Mullerian duct morphology / MGI
- fetal growth retardation / MGI
- fusion of vertebral arches / MGI
- abnormal humerus morphology / MGI
- thoracoschisis / MGI
- perimembraneous ventricular septal defect / MGI
- double ureter / MGI
- abnormal digastric muscle morphology / MGI
- subcutaneous edema / MGI
- abnormal ductus venosus valve morphology / MGI
- abnormal ureter topology / MGI
- abnormal infrahyoid muscle morphology / MGI
- multiple persisting craniopharyngeal ducts / MGI
- reduced sympathetic cervical ganglion size / MGI
- blood in lymph vessels / MGI
- symmetric azygos veins / MGI
- abnormal vertebral artery origin / MGI
- abnormal vertebral artery topology / MGI
- abnormal intestine placement / MGI
- retrolental blood / MGI
- persistent trigeminal artery / MGI