IMPC phenotypes (allele matching)
C57BL/6N-Id2tm2b(EUCOMM)Wtsi/WtsiOulu
| Status | Available to order |
| EMMA ID | EM:14175 |
| International strain name | C57BL/6N-Id2tm2b(EUCOMM)Wtsi/WtsiOulu |
| Alternative name | EPD0977_1_G04 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Id2tm2b(EUCOMM)Wtsi |
| Gene/Transgene symbol | Id2 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from EUCOMM ES clone EPD0977_1_G04. For further details on the construction of this clone see the page at the IMPC portal. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele using a cell permeable HTN-Cre as described in doi:10.1007/s11248-013-9764-x. Click here for more information on EUCOMM final vectors. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | University of Oulu, Oulu, Finland |
Disease and phenotype information
MGI phenotypes (gene matching)
- hydronephrosis / MGI
- small inner medullary pyramid / MGI
- abnormal branching of the mammary ductal tree / MGI
- abnormal olfactory bulb morphology / MGI
- weight loss / MGI
- decreased body size / MGI
- hypoactivity / MGI
- postnatal growth retardation / MGI
- decreased white adipose tissue amount / MGI
- abnormal immune system physiology / MGI
- abnormal lactation / MGI
- abnormal olfaction / MGI
- no abnormal phenotype detected / MGI
- decreased lymph node number / MGI
- abnormal oropharyngeal lymphoid tissue morphology / MGI
- small olfactory bulb / MGI
- absent Peyer's patches / MGI
- no phenotypic analysis / MGI
- loss of dopaminergic neurons / MGI
- premature neuronal precursor differentiation / MGI
- ischuria / MGI
- nervous system phenotype / MGI
- decreased lean body mass / MGI
- abnormal rostral migratory stream morphology / MGI
- abnormal neuronal precursor proliferation / MGI
- abnormal cell differentiation / MGI
- adipose tissue phenotype / MGI
- behavior/neurological phenotype / MGI
- abnormal mammary gland growth during pregnancy / MGI
- absent lymph nodes / MGI
- decreased NK T cell number / MGI
- decreased NK cell number / MGI
- absent NK cells / MGI
- decreased CD8-positive, alpha-beta T cell number / MGI
- abnormal common lymphocyte progenitor cell morphology / MGI
- decreased survivor rate / MGI
- decreased inguinal fat pad weight / MGI
- decreased interscapular fat pad weight / MGI
- distended ileum / MGI
- postnatal lethality, complete penetrance / MGI
- neonatal lethality, incomplete penetrance / MGI
- abnormal ureteropelvic junction morphology / MGI
- ureteropelvic junction stenosis / MGI
- distended jejunum / MGI
- arrhythmic circadian behavior persistence / MGI
- abnormal circadian behavior phase / MGI