FVB-Tg(ACTB-tTS)1Mllo/Cnrm

Status	Available to order
EMMA ID	EM:01415
International strain name	FVB-Tg(ACTB-tTS)1Mllo/Cnrm
Alternative name	pAct-tTS
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(ACTB-tTS)1Mllo
Gene/Transgene symbol	Tg(ACTB-tTS)1Mllo

Information from provider

Provider	Moises Mallo
Provider affiliation	Instituto Gulbenkian de Ciencia
Genetic information	The tTS molecule (a hybrid between the tetracycline repressor, tetR and the KRAB transcriptional repressor) is expressed ubiquitously under the human beta-actin promoter. The construct also contains insulator sequences from the chicken globin locus. This is a transgenic strain to be used in a dual control system to allow repression from promoters carrying tetO (tetracycline operator) sequences. It can be used to produce reversible gene inactivation from tetO-modified loci or to repress the leakiness of tetO promoters when using the tet-ON system.
Phenotypic information	There are no defects associated to this strain.
References	Reversible gene inactivation in the mouse.;Mallo Moisés, Kanzler Benoît, Ohnemus Sabine, ;2003;Genomics;81;356-60; 12676559

Information from EMMA

Archiving centre	CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Literature references

Reversible gene inactivation in the mouse.;Mallo Moisés, Kanzler Benoît, Ohnemus Sabine, ;2003;Genomics;81;356-60; 12676559

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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